{"id":3285,"date":"2020-11-19T17:52:40","date_gmt":"2020-11-19T09:52:40","guid":{"rendered":"http:\/\/dh.oncolab.cn\/index.php\/2020\/11\/19\/pharmacology-therapeutics%ef%bc%9a%e9%9d%92%e8%92%bf%e7%b4%a0%e4%bd%9c%e4%b8%ba%e5%85%8d%e7%96%ab%e7%b3%bb%e7%bb%9f%e8%b0%83%e8%8a%82%e6%8a%97%e8%82%a5%e8%8d%af%e7%9a%84%e6%bd%9c%e5%8a%9b\/"},"modified":"2022-05-01T22:16:28","modified_gmt":"2022-05-01T14:16:28","slug":"pharmacology-therapeutics%ef%bc%9a%e9%9d%92%e8%92%bf%e7%b4%a0%e4%bd%9c%e4%b8%ba%e5%85%8d%e7%96%ab%e7%b3%bb%e7%bb%9f%e8%b0%83%e8%8a%82%e6%8a%97%e8%82%a5%e8%8d%af%e7%9a%84%e6%bd%9c%e5%8a%9b","status":"publish","type":"post","link":"http:\/\/dh.oncolab.cn\/index.php\/2020\/11\/19\/pharmacology-therapeutics%ef%bc%9a%e9%9d%92%e8%92%bf%e7%b4%a0%e4%bd%9c%e4%b8%ba%e5%85%8d%e7%96%ab%e7%b3%bb%e7%bb%9f%e8%b0%83%e8%8a%82%e6%8a%97%e8%82%a5%e8%8d%af%e7%9a%84%e6%bd%9c%e5%8a%9b\/","title":{"rendered":"Pharmacology &amp; Therapeutics\uff1a\u9752\u84bf\u7d20\u4f5c\u4e3a\u514d\u75ab\u7cfb\u7edf\u8c03\u8282\u6297\u80a5\u836f\u7684\u6f5c\u529b"},"content":{"rendered":"<div class=\"wxsyncmain\">\n<p style=\"text-align: center; clear: both; box-sizing: border-box; background-color: #ffffff;\"><span style=\"color: #7a4fd6;\"><span style=\"font-size: 14px;\">\u00a0<\/span><\/span><\/p>\n<p style=\"text-align: left; color: #333333; clear: both; box-sizing: border-box; background-color: #ffffff;\">\n<section style=\"color: #333333; box-sizing: border-box; background-color: #ffffff;\" data-id=\"85559\" data-tools=\"135\u7f16\u8f91\u5668\">\n<section style=\"border-color: #8dadaa; margin: 30px auto 0px; padding: 0px 10px 5px; border-radius: 15px; text-align: center; color: #fefefe; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #8dadaa;\"><span style=\"margin: 0px; padding: 0px; color: #000000; letter-spacing: 0.54px; font-family: \u5b8b\u4f53; font-size: 16px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\u5bfc\u8bfb<\/span><\/p>\n<section style=\"border-color: #8dadaa; margin: 0px 0px 5px; padding: 10px; border-radius: 15px; text-align: left; color: inherit; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #fefefe;\" data-style=\"color: rgb(0, 0, 0);\">\n<p style=\"text-align: left; text-indent: 2em;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px; text-indent: 2em; line-height: 1.6;\">\u9752\u84bf\u7d20\u662f\u8457\u540d\u7684\u6297\u759f\u836f\u7269\uff0c\u8fd1\u671f\u7684\u5927\u91cf\u7814\u7a76\u8bc1\u660e\u4e86\u9752\u84bf\u7d20\u53ca\u5176\u884d\u751f\u7269\u8fd8\u5177\u5907\u6297\u5bc4\u751f\u866b\u3001\u6297\u80bf\u7624\u548c\u6291\u5236\u80a5\u80d6\u7684\u6f5c\u529b\u3002<\/span><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px; text-indent: 2em; line-height: 1.6;\">\u8fd9\u7bc7\u6587\u7ae0\u7740\u91cd\u4ecb\u7ecd\u4e86\u9752\u84bf\u7d20\u7684\u6297\u80a5\u80d6\u6f5c\u529b\uff0c\u5e76\u8ba4\u4e3a\u9752\u84bf\u7d20\u53ef\u4ee5\u901a\u8fc7\u8c03\u8282\u514d\u75ab\u7cfb\u7edf\u8fbe\u5230\u6cbb\u7597\u6cbb\u7597\u80a5\u80d6\u7684\u76ee\u7684\u3002<\/span><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px; text-indent: 2em; line-height: 1.6;\">\u56e0\u6b64\uff0c\u9752\u84bf\u7d20\u5728\u5f53\u524d\u201c\u83b7\u6279\u6297\u80a5\u80d6\u836f\u7269\u8f83\u5c11\u201d\u7684\u80cc\u666f\u4e0b\u6781\u5177\u7814\u7a76\u6f5c\u529b\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: left; color: #333333; text-indent: 0em; clear: both; box-sizing: border-box; background-color: #ffffff;\"><\/section>\n<section style=\"color: #333333; box-sizing: border-box; background-color: #ffffff;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; box-sizing: border-box;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px; padding: 0px; text-indent: 0em; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<section style=\"margin: 0px 10px; padding: 0px; display: flex; max-width: 100%; box-sizing: border-box; justify-content: center; overflow-wrap: break-word;\">\n<section style=\"border-width: 5px 1px 1px; border-style: solid; border-color: #959595; margin: 0px; padding: 5px 20px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\">\n<p style=\"margin: 0px; padding: 0px; text-align: left; letter-spacing: 1.5px; clear: both; min-height: 1em; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"box-sizing: border-box; color: #021eaa; font-family: \u5b8b\u4f53; font-size: 16px; letter-spacing: 0.54px; max-width: 100%; overflow-wrap: break-word; padding: 0px; margin: 0px;\">\u8bba\u6587ID<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"color: #021eaa; padding: 0px; margin: 0px;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"font-size: 16px; padding: 0px; margin: 0px;\">\u539f\u540d\uff1a<\/span><\/strong><\/span><span style=\"color: #000000; font-size: 12pt; text-indent: 0em; line-height: 1.6;\">The potential of artemisinins as anti-obesity agents via modulating theimmune system<\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"color: #021eaa; padding: 0px; margin: 0px;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"font-size: 16px; padding: 0px; margin: 0px;\">\u8bd1\u540d\uff1a<\/span><\/strong><\/span><span style=\"color: black; font-size: 12pt;\">\u9752\u84bf\u7d20\u4f5c\u4e3a\u514d\u75ab\u7cfb\u7edf\u8c03\u8282\u6297\u80a5\u836f\u7684\u6f5c\u529b<\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"color: #021eaa; padding: 0px; margin: 0px;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"font-size: 16px; padding: 0px; margin: 0px;\">\u671f\u520a\uff1a<\/span><\/strong><\/span><span style=\"color: #000000; font-size: 12pt; text-indent: 0em; line-height: 1.6;\">Pharmacology &amp; Therapeutics<\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\"><strong>IF\uff1a<\/strong><\/span><span style=\"color: #000000; font-size: 12pt;\"><span lang=\"EN-US\" style=\"font-size: 12.0pt;\"><span style=\"font-size: 16px;\">10.557<\/span><\/span><\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"color: #021eaa; padding: 0px; margin: 0px;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"font-size: 16px; padding: 0px; margin: 0px;\">\u53d1\u8868\u65f6\u95f4\uff1a<\/span><\/strong><\/span><span style=\"color: #000000; font-size: 16px; padding: 0px; margin: 0px;\">2020.10<\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"color: #021eaa; padding: 0px; margin: 0px;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"font-size: 16px; padding: 0px; margin: 0px;\">\u901a\u8baf\u4f5c\u8005\uff1a<\/span><\/strong><\/span><span style=\"color: #000000; font-size: 12pt;\"><span lang=\"EN-US\" style=\"font-size: 12.0pt;\">\u738b\u7ee7\u521a\uff1b\u5468\u9759<\/span><\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\"><strong>\u901a\u8baf\u4f5c\u8005\u5355\u4f4d\uff1a<\/strong><\/span><span style=\"font-size: 12pt; text-indent: 0em; line-height: 1.6;\">\u4e2d\u56fd\u4e2d\u533b\u79d1\u5b66\u9662\u4e2d\u836f\u7814\u7a76\u6240\u9752\u84bf\u7d20\u7814\u7a76\u4e2d\u5fc3\uff1b<\/span><span style=\"font-size: 12pt; text-indent: 0em; line-height: 1.6;\">\u5e7f\u897f\u533b\u79d1\u5927\u5b66\u57fa\u7840\u533b\u5b66\u9662\u751f\u7406\u5b66\u7cfb<\/span><\/section>\n<section style=\"margin: 0px; padding: 0px; text-align: left; text-indent: 0em; clear: both;\"><span style=\"font-size: 12pt; text-indent: 0em; line-height: 1.6;\">\u00a0<\/span><\/section>\n<section style=\"background-color: #ffffff; box-sizing: border-box; color: #333333;\">\n<section style=\"box-sizing: border-box; max-width: 100%; overflow-wrap: break-word; text-indent: 0em; padding: 0px; margin: 5px 0px 0px 0px;\">\n<section style=\"box-sizing: border-box; display: flex; justify-content: center; max-width: 100%; overflow-wrap: break-word; padding: 0px; margin: 0px 10px 0px 10px;\">\n<section style=\"box-sizing: border-box; max-width: 100%; overflow-wrap: break-word; border-width: 5px 1px 1px 1px; border-color: #959595; border-style: solid; padding: 5px 20px 5px 20px; margin: 0px;\">\n<p style=\"margin: 0px; padding: 0px; text-align: left; letter-spacing: 1.5px; clear: both; min-height: 1em; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"color: #021eaa; font-family: \u5b8b\u4f53; font-size: 16px; letter-spacing: 0.54px; padding: 0px; margin: 0px;\">\u5185\u5bb9<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\">\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">1.\u00a0\u4ecb\u7ecd<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u9752\u84bf\u7d20\u662f\u4ece\u9752\u84bf\u4e2d\u63d0\u53d6\u7684\u500d\u534a\u841c\u4e09\u6c27\u70f7\u5185\u916f\uff0c\u4e2d\u56fd\u7684\u7814\u7a76\u8005\u57281972\u5e74\u8c03\u67e5\u4e86\u5927\u7ea6200\u79cd\u4e2d\u836f\u7684380\u79cd\u63d0\u53d6\u7269\u5e76\u5bf9\u5c0f\u9f20\u8fdb\u884c\u6297\u759f\u5b9e\u9a8c\uff0c\u6700\u7ec8\u9752\u84bf\u7d20\u83b7\u5f97\u4e86\u6210\u529f\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u53cc\u6c22\u9752\u84bf\u7d20\uff08DHA\uff09\u6bd4\u9752\u84bf\u7d20\u5177\u6709\u66f4\u7a33\u5b9a\u7684\u7ed3\u6784\u548c\u66f4\u597d\u7684\u6297\u759f\u6d3b\u6027\u3002\u9752\u84bf\u7425\u916f\u56e0\u5176\u6c34\u6eb6\u6027\u597d\u3001\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u9ad8\u800c\u5907\u53d7\u5173\u6ce8\u3002\u9752\u84bf\u7425\u916f\u3001\u84bf\u7532\u919a\u548c\u84bf\u919a\u540c\u5c5e\u4e8e\u9752\u84bf\u7d20\u884d\u751f\u7269\uff0c\u5bf9\u759f\u75be\u6cbb\u7597\u6709\u6548\uff08\u56fe1\uff09\u3002\u4eba\u4eec\u5bf9\u5f00\u53d1\u66f4\u6709\u6548\u7684\u9752\u84bf\u7d20\u884d\u751f\u7269\u7684\u5174\u8da3\u548c\u52aa\u529b\u8d8a\u6765\u8d8a\u5927\uff0c\u622a\u81f3\u76ee\u524d\uff0c\u9752\u84bf\u7d20\u5df2\u88ab\u7528\u4e8e\u6cbb\u7597\u764c\u75c7\u3001\u75c5\u6bd2\u6216\u5bc4\u751f\u866b\u76f8\u5173\u611f\u67d3\u7b49\u708e\u75c7\u6027\u75be\u75c5\u3002<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u80a5\u80d6\u75c7\u662f\u7531\u4e8e\u957f\u671f\u80fd\u91cf\u6d88\u8017\u51cf\u5c11\u548c\u98df\u7269\u6444\u5165\u589e\u957f\u5f15\u8d77\u7684\u3002\u8fc7\u53bb\u4e09\u5341\u5e74\u6765\uff0c\u5168\u7403\u80a5\u80d6\u7387\u5927\u5e45\u4e0a\u5347\u5e76\u6210\u4e3a\u53d1\u5c55\u4e2d\u56fd\u5bb6\u548c\u53d1\u8fbe\u56fd\u5bb6\u7684\u4e3b\u8981\u6d41\u884c\u75c5\u3002\u7edd\u5927\u591a\u6570\u80a5\u80d6\u60a3\u8005\u8868\u73b0\u51fa\u8f83\u5dee\u7684\u5065\u5eb7\u72b6\u51b5\u662f\u56e0\u4e3a\u5408\u540c\u65f6\u60a3\u67092\u578b\u7cd6\u5c3f\u75c5\u548c\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u7b49\u75be\u75c5\u3002\u9664\u4ee3\u8c22\u7efc\u5408\u5f81\u5916\uff0c\u80a5\u80d6\u4eba\u7fa4\u4e2d\u67d0\u4e9b\u7c7b\u578b\u764c\u75c7\uff08\u5982\u5b50\u5bab\u5185\u819c\u764c\u548c\u98df\u7ba1\u817a\u764c\uff09\u7684\u53d1\u75c5\u7387\u8981\u9ad8\u5f97\u591a\u3002\u6b64\u5916\uff0c\u80a5\u80d6\u53ef\u80fd\u589e\u52a0\u75f4\u5446\u3001\u6291\u90c1\u548c\u7126\u8651\u7b49\u795e\u7ecf\u7cbe\u795e\u75be\u75c5\u7684\u60a3\u75c5\u7387\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages js_insertlocalimg\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-99581139b8e6952fbcf36c5660cfe1e7.jpeg\" data-ratio=\"1.40703125\" data-s=\"300,640\" data-type=\"jpeg\" data-w=\"1280\" \/><\/p>\n<section style=\"margin: 0px; padding: 0px; text-align: center; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; text-indent: 0em; background-color: #ffffff;\"><strong style=\"text-indent: 32px; text-align: center; line-height: 1.6;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px; line-height: 150%;\">\u56fe1\u00a0\u9752\u84bf\u7d20\u53ca\u5176\u884d\u751f\u7269<\/span><\/strong><\/section>\n<p style=\"text-align: center; color: #333333; clear: both; box-sizing: border-box; margin: 0px; padding: 0px; max-width: 100%; overflow-wrap: break-word; background-color: #ffffff;\"><strong style=\"padding: 0px; margin: 0px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px; line-height: 150%; padding: 0px; margin: 0px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">2.\u00a0\u9752\u84bf\u7d20\u7684\u6784\u6548\u5173\u7cfb<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u9752\u84bf\u7d20\u662f\u4e00\u79cd\u534a\u841c\u5316\u5408\u7269\uff0c\u7531\u534a\u7f29\u916e\u3001\u534a\u7f29\u919b\u548c\u5185\u916f\u7ec4\u6210\u30021,2,4-\u4e09\u6c27\u70f7\u7cfb\u7edf\u5185\u7684\u5185\u8fc7\u6c27\u5316\u7269\u952e\u88ab\u8ba4\u4e3a\u662f\u5904\u7406\u5176\u6297\u759f\u4f5c\u7528\u7684\u5173\u952e\u7ed3\u6784\uff08\u56fe1\uff09\u3002\u759f\u539f\u866b\u901a\u8fc7\u9176\u964d\u89e3\u5bbf\u4e3b\u6db2\u6ce1\u4e2d\u7ea2\u7ec6\u80de\u7684\u8840\u7ea2\u86cb\u767d\u6765\u83b7\u5f97\u6c28\u57fa\u9178\u3002\u9752\u84bf\u7d20\u53ca\u5176\u884d\u751f\u7269\u7684\u4f5c\u7528\u673a\u5236\uff08MOA\uff09\u4e3b\u8981\u662f\u901a\u8fc7\u4ea7\u751f\u6d3b\u6027\u6c27\uff08ROS\uff09\u548c\u78b3\u4e2d\u5fc3\u81ea\u7531\u57fa\u6765\u9a71\u52a8\u5176\u6297\u759f\u6d3b\u6027\u3002\u9752\u84bf\u7d20\u5bf9\u767d\u8272\u8102\u80aa\u7ec6\u80de\u7684MOA\u4e0e\u6297\u759f\u4f5c\u7528\u673a\u5236\u76f8\u4f3c\u3002\u5728\u524d\u5217\u817a\u764c\u7ec6\u80de\uff08LNCaP\uff09\u548c\u4eba\u7c7b\u4e73\u817a\u764c\u7ec6\u80de\uff08MCF7\uff09\u4e2d\uff0cG1\u7ec6\u80de\u5468\u671f\u963b\u6ede\u662f\u9752\u84bf\u7d20\u901a\u8fc7\u8bf1\u5bfc\u6291\u5236\u7ec6\u80de\u589e\u6b96\u7684\u4e3b\u8981\u8fc7\u7a0b\u3002\u5728\u53e6\u4e00\u4e2a\u524d\u5217\u817a\u764c\u7ec6\u80de\u7cfbDU145\u4e2d\uff0c\u9752\u84bf\u7425\u916f\u901a\u8fc7\u5207\u5272\u524d\u86cb\u767d\u91763\u548c9\u4fc3\u8fdbcaspase\u4f9d\u8d56\u6027\u51cb\u4ea1\u3002\u9752\u84bf\u7d20\u53ef\u4e0b\u8c03MMP2\uff08\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176-2\uff09\u6c34\u5e73\uff0c\u5e76\u963b\u65ad\u4eba\u9ed1\u8272\u7d20\u7624\u7ec6\u80deA375M\u7684\u7ec6\u80de\u8fc1\u79fb\u3002DHA\u901a\u8fc7\u6838\u56e0\u5b50\u03baB\uff08NF-\u03baB\uff09\u4fe1\u53f7\u901a\u8def\u6291\u5236\u4eba\u7c7b\u5375\u5de2\u764c\u7ec6\u80de\u548c\u80f0\u817a\u764c\u7ec6\u80de\u7684\u8f6c\u79fb\u3002\u9752\u84bf\u7d20\u8fd8\u5177\u6709\u6297\u75c5\u6bd2\u3001\u6297\u5bc4\u751f\u866b\u548c\u6297\u771f\u83cc\u6d3b\u6027\u3002\u9752\u84bf\u7425\u916f\u80fd\u4e0b\u8c03\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u590d\u5236\u6c34\u5e73\u3002\u6b64\u5916\uff0c\u9752\u84bf\u7d20\u884d\u751f\u7269\uff08\u5305\u62ec\u84bf\u7532\u919a\u3001DHA\u548c\u84bf\u919a\uff09\u53ef\u4ee5\u9ad8\u6548\u6291\u5236\u9690\u7403\u83cc\u7684\u589e\u6b96\u3002\u73af\u6c27\u70f7\u53ef\u80fd\u4e0e\u6297\u75c5\u6bd2\u3001\u6297\u771f\u83cc\u4ee5\u53ca\u4ea7\u751f\u81ea\u7531\u57fa\u6740\u706d\u75c5\u539f\u4f53\u7684\u80fd\u529b\u6709\u5173\u3002\u6b64\u5916\uff0c\u5b83\u4eec\u53ef\u80fd\u901a\u8fc7\u6291\u5236\u70df\u9170\u80fa\u817a\u560c\u5464\u4e8c\u6838\u82f7\u9178\u8131\u6c22\u9176\uff08NADH\uff09\u800c\u7834\u574f\u75c5\u539f\u4f53\u7684\u7ebf\u7c92\u4f53\u529f\u80fd\u3002\u91cd\u8981\u7684\u662f\uff0c\u9752\u84bf\u7d20\u5df2\u5728\u591a\u79cd\u708e\u75c7\u75be\u75c5\u6a21\u578b\u4e2d\u8fdb\u884c\u4e86\u7814\u7a76\uff0c\u56e0\u4e3a\u5b83\u4eec\u5177\u6709\u826f\u597d\u7684\u836f\u7406\u5b66\u7279\u6027\u548c\u5bf9\u591a\u79cd\u7ec6\u80de\u9014\u5f84\u7684\u5b89\u5168\u6027\u3002\u9752\u84bf\u7425\u916f\u6700\u65e9\u662f\u5728\u4eba\u5916\u5468\u8840\u6dcb\u5df4\u7ec6\u80de\u548c\u5c0f\u9f20\u813e\u7ec6\u80de\u4e2d\u4f5c\u4e3a\u514d\u75ab\u6291\u5236\u5242\u8fdb\u884c\u7814\u7a76\u3002\u6b64\u5916\uff0c\u9752\u84bf\u7425\u916f\u53ef\u901a\u8fc7\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\uff08TNF\uff09\u53d7\u4f53\u76f8\u5173\u56e0\u5b50\uff08TRAF\uff09-Beclin1-PI3KC3\u9014\u5f84\u6291\u5236\u81ea\u566c\u6fc0\u6d3b\uff0c\u4ece\u800c\u6291\u5236\u8102\u591a\u7cd6\uff08LPS\uff09\u8bf1\u5bfc\u7684\u5de8\u566c\u7ec6\u80de\u91ca\u653e\u7ec6\u80de\u56e0\u5b50\u3002<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u00a0<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">3. \u4e0d\u540c\u75c5\u7406\u72b6\u6001\u4e0b\u4ee3\u8c22\u5f39\u6027\u7684\u5173\u952e\u56e0\u7d20\u53ca\u673a\u5236<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u8102\u80aa\u7ec6\u80de\u88ab\u89c6\u4e3a\u80fd\u91cf\u50a8\u5b58\u5e93\u548c\u514d\u75ab\u5668\u5b98\u3002\u8102\u80aa\u7ec6\u80de\u4e3b\u8981\u6709\u4e24\u79cd\u7c7b\u578b\uff1a\u767d\u8272\u8102\u80aa\u7ec6\u80de\uff08WAT\uff09\u548c\u68d5\u8272\u8102\u80aa\u7ec6\u80de\uff08BAT\uff09\u3002BAT\u7684\u529f\u80fd\u4e3b\u8981\u5305\u62ec\u80fd\u91cf\u6d88\u8017\u8c03\u8282\u548c\u517c\u6027\u4ea7\u70ed\uff0c\u800cWAT\u5728\u50a8\u80fd\u4e2d\u8d77\u7740\u91cd\u8981\u4f5c\u7528\u3002\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u8868\u660e\u80a5\u80d6\u4e0d\u4ec5\u4e0e\u5148\u5929\u514d\u75ab\u6709\u5173\uff0c\u800c\u4e14\u4e0e\u9002\u5e94\u6027\u514d\u75ab\u6709\u5173\uff08\u56fe2\uff09\u3002\u9664\u8102\u80aa\u7ec4\u7ec7\u4e2d\u7684TNF-\u03b1\u5916\uff0c\u80a5\u80d6\u60a3\u8005\u4f53\u5185\u7684\u4e00\u4e9b\u708e\u75c7\u6027\u7ec6\u80de\u56e0\u5b50\u4e5f\u6709\u6240\u589e\u52a0\uff0c\u5305\u62ec\u767d\u7ec6\u80de\u4ecb\u7d20\uff08IL\uff09-6\u3001IL-1\u03b2\u3001\u8d8b\u5316\u56e0\u5b50\uff08Csingle bondC motif\uff09\u914d\u4f532\uff08CCL2\uff09\uff0c\u8fd9\u4e9b\u53ef\u80fd\u662f\u80a5\u80d6\u7684\u4e3b\u8981\u8bf1\u56e0\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages js_insertlocalimg\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-07bafaed9cc8c080c248d80f7911ffb4.jpeg\" data-ratio=\"1.2015625\" data-s=\"300,640\" data-type=\"jpeg\" data-w=\"1280\" \/><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: center; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; text-indent: 0em; background-color: #ffffff;\"><strong style=\"text-indent: 32px; text-align: center; line-height: 1.6;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px; line-height: 150%;\">\u56fe2\u00a0\u80a5\u80d6\u5bfc\u81f4\u708e\u75c7\u7684\u539f\u56e0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: center; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; text-indent: 0em; background-color: #ffffff;\"><strong style=\"text-indent: 32px; text-align: center; line-height: 1.6;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px; line-height: 150%;\">Treg\u7ec6\u80de\u548cM2\u5de8\u566c\u7ec6\u80de\u8868\u73b0\u51fa\u8f83\u9ad8\u7684\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u3002\u5f53\u66b4\u9732\u4e8e\u8fc7\u591a\u7684\u8425\u517b\u7269\u8d28\u65f6\uff0c\u8102\u80aa\u7ec4\u7ec7\u4e2d\u6709\u80a5\u5927\u7684\u8102\u80aa\u7ec6\u80de\u3002\u80a5\u80d6\u8102\u80aa\u7ec4\u7ec7\u4e2d\uff0c\u4fc3\u708e\u6027M1\u5de8\u566c\u7ec6\u80de\u4e0e\u6297\u708eM2\u548c\u81ea\u7136\u6740\u4f24\u7ec6\u80de\uff08NK\uff09\u7684\u6d78\u6da6\u7387\u8f83\u9ad8\uff0cTreg\u7ec6\u80de\u6570\u91cf\u4e5f\u51cf\u5c11\u3002<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: center; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; text-indent: 0em; background-color: #ffffff;\"><strong style=\"text-indent: 32px; text-align: center; line-height: 1.6;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px; line-height: 150%;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">4.\u00a0\u80a5\u80d6\u60a3\u8005\u6162\u6027\u708e\u75c7\u4e0e\u80f0\u5c9b\u7d20\u62b5\u6297\uff08IR\uff09<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u80f0\u5c9b\u7d20\u62b5\u6297\u662f\u7cd6\u5c3f\u75c5\u65e9\u671f\u7684\u7279\u5f81\uff0c\u4e5f\u662f\u80f0\u5c9b\u7d20\u7684\u8131\u654f\u53cd\u5e94\u4e4b\u4e00\u3002\u5728\u5065\u5eb7\u72b6\u6001\u4e0b\uff0c\u708e\u75c7\u53ef\u80fd\u662f\u4e00\u4e2a\u77ed\u671f\u6216\u6025\u6027\u8fc7\u7a0b\u3002\u7136\u800c\uff0c\u5f53\u708e\u75c7\u6301\u7eed\u5f88\u957f\u4e00\u6bb5\u65f6\u95f4\u65f6\u4f1a\u5bfc\u81f4\u5982IR\u8fd9\u6837\u7684\u7834\u574f\u6027\u5f71\u54cd\uff0c\u56e0\u4e3a\u708e\u75c7\u53cd\u5e94\u5728\u5206\u89e3\u4ee3\u8c22\u8fc7\u7a0b\u800c\u4e0d\u662f\u5408\u6210\u4ee3\u8c22\u8fc7\u7a0b\u4e2d\u8d77\u4f5c\u7528\u3002\u5728IR\u72b6\u6001\u4e0b\uff0c\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u589e\u52a0\uff0c\u6297\u708e\u56e0\u5b50\u51cf\u5c11\u3002\u80f0\u5c9b\u7d20\u62b5\u6297\u7684\u673a\u5236\u4e4b\u4e00\u662f\uff1a\u8102\u80aa\u7ec6\u80de\u4e2d\u8fc7\u591a\u7684\u708e\u6027\u7ec6\u80de\u56e0\u5b50\u8bf1\u5bfc\u4e86\u80f0\u5c9b\u7d20\u53d7\u4f53\u5e95\u72691\uff08IRS-1\uff09\u4e0a\u7684\u4e1d\u6c28\u9178\u7684\u78f7\u9178\u5316\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u963b\u65ad\u4e86\u916a\u6c28\u9178\u7684\u78f7\u9178\u5316\uff0c\u8fdb\u800c\u5bfc\u81f4\u80f0\u5c9b\u7d20\u4fe1\u53f7\u901a\u8def\u53d7\u635f\u3002<\/span><\/p>\n<p style=\"margin: 0px; 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padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u00a0<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">8.\u00a0\u9752\u84bf\u7d20\u5728\u5e7f\u8c31\u75be\u75c5\u6cbb\u7597\u4e2d\u7684\u4e89\u8bae<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u5c3d\u7ba1\u9752\u84bf\u7d20\u5df2\u7ecf\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e86\u51e0\u5341\u5e74\uff0c\u4f46\u5176\u5177\u4f53\u4f5c\u7528\u673a\u5236\u4ecd\u4e0d\u6e05\u695a\u3002\u6709\u8bc1\u636e\u8868\u660e\uff0c\u9752\u84bf\u7d20\u901a\u8fc7\u4e0e\u7ec6\u80de\u86cb\u767d\u7684\u591a\u9776\u70b9\u548c\u6df7\u6742\u76f8\u4e92\u4f5c\u7528\u8868\u73b0\u51fa\u6297\u708e\u4f5c\u7528\u3002\u5728\u6297\u759f\u75be\u6cbb\u7597\u4e2d\uff0c\u9752\u84bf\u7d20\u7684\u6f5c\u5728\u9776\u70b9\u5305\u62ec\u8840\u7ea2\u7d20\u3001\u9ab6\u9aa8\/\u5185\u8d28\u7f51Ca2+-ATP\u9176\uff08PfATP6\uff09\u4ee5\u53ca\u5bc4\u751f\u866b\u819c\u3002\u5728\u764c\u75c7\u4e2d\uff0c\u9752\u84bf\u7d20\u7684\u6f5c\u5728\u9776\u70b9\u5305\u62ec\u7ffb\u8bd1\u63a7\u5236\u80bf\u7624\u86cb\u767d\uff08hTCTP\uff09\u3001\u6076\u6027\u80bf\u76242\uff08PfFP2\uff09\u3001\u5bcc\u7ec4\u6c28\u9178\u86cb\u767d\uff08PfHRP-2\uff09\u3001\u819c\u8c37\u80f1\u7518\u80bdS-\u8f6c\u79fb\u9176\uff08PfMGST\uff09\uff0c\u4ee5\u53ca\u78f7\u8102\u9170\u808c\u9187-3-\u6fc0\u9176\uff08PfPI3K\uff09\u3002\u5728HeLa\u764c\u7ec6\u80de\u86cb\u767d\u8d28\u7ec4\u5b66\u4e2d\uff0c\u63d0\u793a\u9752\u84bf\u7d20\u901a\u8fc7\u5171\u4ef7\u4fee\u9970\uff0c\u901a\u8fc7\u9752\u84bf\u7d20\u63a2\u9488\u8c03\u63a7\u591a\u4e2a\u7ec6\u80de\u9776\u70b9\uff0c\u8868\u73b0\u51fa\u534f\u540c\u7684\u6297\u764c\u6cbb\u7597\u4f5c\u7528\u3002<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u4e0e\u767d\u85dc\u82a6\u9187\u548c\u4e8c\u7532\u53cc\u80cd\u5bf9\u673a\u4f53\u7684\u591a\u6f5c\u80fd\u4f5c\u7528\u4e00\u6837\uff0c\u9752\u84bf\u7d20\u5728\u5c0f\u9f20\u548c\u9175\u6bcd\u4e2d\u5145\u5f53SIRT1\u6216AMPK\u7684\u6fc0\u6d3b\u5242\u3002\u6b64\u524d\u7684\u4e00\u4efd\u62a5\u544a\u663e\u793a\uff0c\u9752\u84bf\u7d20\u7684\u4f4e\u5242\u91cf\u548c\u957f\u671f\u6cbb\u7597\u6709\u53ef\u80fd\u6e05\u9664\u81ea\u7531\u57fa\uff0c\u81ea\u7531\u57fa\u4f1a\u7834\u574f\u9752\u84bf\u7d20\u5185\u7684\u5185\u8fc7\u6c27\u5316\u7269\u6865\uff0c\u5bfc\u81f4\u9752\u84bf\u7d20\u7684\u6548\u7387\u964d\u4f4e\u3002\u7531\u4e8e\u9752\u84bf\u7d20\u7684\u591a\u9776\u70b9\u548c\u6df7\u6742\u9776\u5411\u7279\u6027\uff0c\u9752\u84bf\u7d20\u7684\u751f\u7269\u6d3b\u6027\u53ef\u80fd\u662f\u5e7f\u8c31\u7684\u3001\u975e\u7279\u5f02\u6027\u7684\uff0c\u4ece\u800c\u5bfc\u81f4\u610f\u60f3\u4e0d\u5230\u7684\u4ee3\u8c22\u7d0a\u4e71\u6216\u5f02\u5e38\u3002\u4f8b\u5982\uff0c\u7814\u7a76\u53d1\u73b0\u9752\u84bf\u7d20\u5bf9\u819c\u8102\u548cDNA\u7684\u6c27\u5316\u635f\u4f24\u5bfc\u81f4\u751f\u6b96\u6bd2\u6027\u3002\u7531\u4e8e\u5728\u52a8\u7269\u7814\u7a76\uff08\u5305\u62ec\u7334\u5b50\u3001\u5154\u5b50\u548c\u5927\u9f20\uff09\u4e2d\u89c2\u5bdf\u5230\u80da\u80ce\u6bd2\u6027\uff0c\u4ee5\u9752\u84bf\u7d20\u4e3a\u57fa\u7840\u7684\u8054\u5408\u7597\u6cd5\u5df2\u88ab\u7981\u6b62\u7528\u4e8e\u5b55\u5987\u3002\u867d\u7136\u5f88\u96be\u4ece\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u6536\u96c6\u6570\u636e\u6765\u603b\u7ed3\u9752\u84bf\u7d20\u7684\u6f5c\u5728\u751f\u6b96\u6bd2\u6027\uff0c\u4f46\u9700\u8981\u5f00\u53d1\u514b\u670d\u6216\u907f\u514d\u8fd9\u4e9b\u963b\u788d\u7684\u6280\u672f\u3002\u9752\u84bf\u7425\u916f\u8f7d\u836f\u7cfb\u7edf\uff0c\u5982\u805a\uff08D\uff0cL-\u4e73\u9178-\u7f9f\u57fa\u4e59\u9178\uff09\uff08PLGA\uff09\u7eb3\u7c73\u9897\u7c92\u5df2\u88ab\u62a5\u9053\u53ef\u63d0\u9ad8\u6297\u759f\u539f\u866b\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u6709\u8da3\u7684\u662f\uff0c\u6709\u4eba\u89c2\u5bdf\u5230\u4e00\u79cd\u5f00\u53d1\u7684DHA\u7c7b\u4f3c\u7269\u5177\u6709\u663e\u8457\u7684\u4f53\u5185\u5916\u6297\u5375\u5de2\u764c\u6d3b\u6027\uff0c\u4f46\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u6bd2\u6027\u8f83\u4f4e\u3002\u8fd9\u4e9b\u9752\u84bf\u7d20\u884d\u751f\u7269\u7ed3\u5408\u6216\u5305\u88ab\u836f\u7269\u4e3a\u5f00\u53d1\u6297\u80a5\u80d6\u836f\u7269\u7684\u5148\u5bfc\u5316\u5408\u7269\u63d0\u4f9b\u4e86\u5f88\u6709\u524d\u9014\u7684\u89c1\u89e3\u3002<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u867d\u7136\u6539\u5584\u996e\u98df\u548c\u751f\u6d3b\u65b9\u5f0f\u6709\u52a9\u4e8e\u51cf\u8f7b\u80a5\u80d6\uff0c\u4f46\u8fd9\u4e5f\u53d6\u51b3\u4e8e\u8fd9\u4e9b\u884c\u4e3a\u7684\u957f\u671f\u5f71\u54cd\u3002\u76ee\u524d\uff0c\u6709\u6548\u7684\u51cf\u80a5\u548c\u964d\u7cd6\u7b56\u7565\u5305\u62ec\u57fa\u4e8e\u8102\u80aa\u56e0\u5b50\u7684\u6cbb\u7597\u3001\u4fc3\u8fdb\u8102\u80aa\u8910\u53d8\u3001\u8c03\u8282\u7f3a\u6c27\u3001\u7ea4\u7ef4\u5316\u548c\u708e\u75c7\u3002\u4f46FDA\u5df2\u6279\u51c6\u957f\u671f\u670d\u7528\u6bd4\u514b\u8212\u5c14\u6216\u8212\u514b\u4e50\u6cbb\u7597\u7cd6\u5c3f\u75c5\uff0c\u4f46\u957f\u671f\u7597\u6548\u4e0d\u4f73\u3002\u4f5c\u4e3aIKK\u03b5\u6216TBK1\u6291\u5236\u5242\u3001GPR120\u6fc0\u52a8\u5242\u548cCCR2\u62ee\u6297\u5242\u7684\u836f\u7269\u6b63\u5728\u8fdb\u884c\u80a5\u80d6\u75c7\u62162\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7597\u7684\u4e34\u5e8a\u524d\u6216\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5206\u522b\u901a\u8fc7\u51cf\u5c11WAT\u708e\u75c7\u3001\u51cf\u5c11WAT\u6d78\u6da6\u548c\u963b\u65ad\u5de8\u566c\u7ec6\u80de\u8fdb\u5165WAT\u7684\u6d41\u52a8\u6027\u3002\u8bb8\u591a\u7814\u7a76\u8868\u660e\uff0c\u9752\u84bf\u7d20\u53ca\u5176\u884d\u751f\u7269\u5728\u4f53\u5185\u3001\u4f53\u5916\u548c\u6a21\u578b\u4e2d\u5747\u8868\u73b0\u51fa\u8f83\u5f3a\u7684\u514d\u75ab\u6291\u5236\u4f5c\u7528\u3002\u672a\u6765\u7684\u5de5\u4f5c\u5e94\u8be5\u4e3b\u8981\u8c03\u67e5\u9752\u84bf\u7d20\u5728\u80a5\u80d6\u548c\u7cd6\u5c3f\u75c5\u6cbb\u7597\u4e2d\u7684\u5242\u91cf\u3001\u7597\u6548\u3001\u5438\u6536\u548c\u6162\u6027\u66b4\u9732\u3002<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u00a0<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">9.\u00a0\u7ed3\u8bba\u4e0e\u5c55\u671b<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; color: #333333; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><strong><span style=\"margin: 0px; padding: 0px; color: #021eaa; font-size: 16px;\">\u00a0<\/span><\/strong><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u9752\u84bf\u7d20\u5177\u6709\u6297\u764c\u3001\u6297\u83cc\u3001\u6297\u75c5\u6bd2\u3001\u6297\u5bc4\u751f\u866b\u3001\u6297\u8fc7\u654f\u3001\u6297\u708e\u7b49\u591a\u79cd\u6d3b\u6027\u3002\u80a5\u80d6\u60a3\u8005\u7684\u8102\u80aa\u7ec6\u80de\u529f\u80fd\u969c\u788d\u4e0e\u8102\u548c\u7cd6\u4ee3\u8c22\u53d7\u635f\u3001\u8102\u80aa\u56e0\u5b50\u5206\u6ccc\u6a21\u5f0f\u6539\u53d8\u4ee5\u53ca\u5c40\u90e8\u548c\u5168\u8eab\u708e\u75c7\u6709\u5173\uff0c\u5148\u5929\u514d\u75ab\u548c\u9002\u5e94\u6027\u514d\u75ab\u90fd\u4e0e\u8102\u80aa\u7ec4\u7ec7\u708e\u75c7\u6709\u5173\u3002\u901a\u8fc7MAPK\u3001PI3K\/Akt\u3001\u78f7\u8102\u9176C\u03b3\u3001NF-\u03baB\u3001Toll\u6837\u53d7\u4f53\u3001Nrf2\/ARE\u3001Akt\/Bcl2\u3001ERK1\/2\u3001Ras\u548cWnt\/\u03b2-catenin\u4fe1\u53f7\u901a\u8def\u7684\u62ee\u6297\u5242\u6765\u8bc4\u4f30\u9752\u84bf\u7d20\u7684\u4fc3\u708e\u75c7\u4f5c\u7528\u3002\u57fa\u4e8e\u590d\u6742\u7684\u514d\u75ab\u4ee3\u8c22\u4fe1\u53f7\u7f51\u7edc\uff0c\u8fd9\u7bc7\u6587\u7ae0\u7efc\u8ff0\u4e86\u9752\u84bf\u7d20\u901a\u8fc7\u4e0e\u4fe1\u53f7\u7f51\u7edc\u76f8\u4e92\u4f5c\u7528\u8c03\u8282\u4ee3\u8c22\u7a33\u6001\u7684\u673a\u5236\u3002\u6b64\u5916\uff0c\u9752\u84bf\u7d20\u8fd8\u53c2\u4e0e\u591a\u79cd\u514d\u75ab\u53cd\u5e94\u7684\u8c03\u8282\uff0c\u5982\u5de8\u566c\u7ec6\u80de\u6d3b\u5316\u3001T\u7ec6\u80de\u6d3b\u5316\u4e0e\u589e\u6b96\u3001T\u7ec6\u80de\u4e9a\u7fa4\u5206\u5316\u7b49\uff0c\u7531\u4e8e\u9752\u84bf\u7d20\u901a\u8fc7\u4f5c\u7528\u4e8e\u591a\u79cd\u6210\u5206\u800c\u5728\u708e\u75c7\u4e2d\u5177\u6709\u514d\u75ab\u6291\u5236\u4f5c\u7528\uff0c\u8fd9\u4e3a\u901a\u8fc7\u514d\u75ab\u8c03\u8282\u6cbb\u7597\u80a5\u80d6\u548c\u7cd6\u5c3f\u75c5\u7b49\u591a\u79cd\u4ee3\u8c22\u6027\u75be\u75c5\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u7b56\u7565\u3002\u6b64\u5916\uff0c\u751f\u7269\u7b56\u7565\u4e0e\u86cb\u767d\u8d28\u7ec4\u5b66\u76f8\u7ed3\u5408\u6709\u52a9\u4e8e\u9610\u660e\u9752\u84bf\u7d20\u7684\u4f5c\u7528\u673a\u5236\uff0c\u4fc3\u8fdb\u5bfb\u627e\u6cbb\u7597\u4ee3\u8c22\u6027\u75be\u75c5\u7684\u836f\u7269\u9776\u70b9\u3002<\/span><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53; font-size: 16px;\">\u00a0<\/span><\/p>\n<p style=\"line-height: 150%;\"><span style=\"font-size: 16px; line-height: 150%;\">\u00a0<\/span><strong style=\"text-align: left; text-indent: 2em; max-width: 100%; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; font-size: 20px; letter-spacing: 0.544px; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5f80\u671f\u6587\u7ae0\u63a8\u8350<\/strong><\/p>\n<p style=\"line-height: 150%;\"><a style=\"text-indent: 2em; text-align: left; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245082&amp;idx=1&amp;sn=7cb0b8f302f6746066637f7abfc576ef&amp;chksm=8d748c9bba03058d81ec66f0da9a87ebbff4088e871524e32cf318c3dbe67fb1e1b2de6ad417&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><span style=\"text-indent: 2em; text-align: left;\">\u00a0<\/span><\/p>\n<p style=\"line-height: 150%;\"><span style=\"text-indent: 2em; text-align: left;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245110&amp;idx=1&amp;sn=8000cce43687dc9eedbe26bf005e7883&amp;chksm=8d748cb7ba0305a1003f3a18c8a3631b8787ff4b2f19559bdfb2ede464b374c289634592c525&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"11\" data-linktype=\"2\">\u79d1\u7814 | Cell Metab.\uff1a\u8102\u8d28\u4ee3\u8c22\u5728\u764c\u75c7\u4e2d\u7684\u4f5c\u7528<\/a><br \/>\n<\/span><\/p>\n<p style=\"line-height: 150%;\"><span style=\"text-indent: 2em; text-align: left;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245106&amp;idx=1&amp;sn=9f42d68722f6120ee1e88a0ee3ff9cc3&amp;chksm=8d748cb3ba0305a5258983ab77761a62ead37dc231c5c019c281edd848dfa85b2962e7805e25&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"11\" data-linktype=\"2\">\u7efc\u8ff0 | \u5fae\u751f\u7269-\u80a0-\u8111\u8f74\uff1a\u4e2d\u67a2\u795e\u7ecf\u75be\u75c5\u65b0\u7684\u6cbb\u7597\u601d\u8def<\/a><br \/>\n<\/span><\/p>\n<p style=\"line-height: 150%;\"><a style=\"text-indent: 2em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244984&amp;idx=1&amp;sn=9203285637478abe17fea957bb4a4b3c&amp;chksm=8d748d39ba03042fceb79cdd77d520d07e613fc04f9be12fb7a759b7fb11b0581066a81689e0&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">BD LSR Fortessa\u6d41\u5f0f-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244984&amp;idx=2&amp;sn=ca672f89970541c6688cbb47d25ee379&amp;chksm=8d748d39ba03042f5707584ba5568c835db80604229d09f6bc322ef9f567bac3005ba771b06c&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">BD Accuri C5\u6d41\u5f0f\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244479&amp;idx=1&amp;sn=7b577b34dc059d84b6330ca9d307e813&amp;chksm=8d748f3eba030628f0525ced9a39e1d8333288be7d4886ff71cb9c0d3354bcdeee99c9126fe4&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">BD FACSJAZZ\u6d41\u5f0f\u7ec6\u80de\u5206\u9009\u4eea\u57fa\u672c\u53c2\u6570\u53ca\u5e94\u7528\u7b80\u4ecb<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244468&amp;idx=1&amp;sn=f21f2d1f9b0c28d542d9cc22ab188c8f&amp;chksm=8d748f35ba0306231171b9b0483f6f8529290597e4838c97e7facca928ab176b05d1aa0ed2e2&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">BD Accuri C5\u6d41\u5f0f\u7ec6\u80de\u4eea\u4f7f\u7528\u89c4\u8303\u53ca\u64cd\u4f5c\u6d41\u7a0b<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245067&amp;idx=1&amp;sn=f6c737e518a915bb049d238672b3bbbc&amp;chksm=8d748c8aba03059c25cf2438f49a31f98a497aaab659b840076649f8a652e4b1797ca5ce8c05&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u514d\u75ab\u8367\u5149\u5b9e\u9a8c-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245033&amp;idx=1&amp;sn=b366528abeb3829a731382b3978109f6&amp;chksm=8d748ce8ba0305fefcc4b8cf17c9c5b5ff3ebbfc663c3fbf51c276b7fd75895c7a13affe6d81&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">WB\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245098&amp;idx=1&amp;sn=0faf5a71d7f4a2df2dd10b0dd3515e47&amp;chksm=8d748cabba0305bdb52ba683d76a20f5494cf029fe18895a5c875825223e6feeb7d2b381cd9b&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">Annexin V\/PI\u67d3\u8272\u68c0\u6d4b\u7ec6\u80de\u51cb\u4ea1-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244905&amp;idx=1&amp;sn=9e75242aa7a3bbc991e76d7987f0b503&amp;chksm=8d748d68ba03047e146a11c1337eb57a148665f60dc7c4bb429d3abe72b6241f430444142218&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u8521\u53f8LSM800\u6fc0\u5149\u5171\u805a\u7126\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244905&amp;idx=2&amp;sn=12a088d6ecc91e9b33a922c3df9a14c6&amp;chksm=8d748d68ba03047ee6e4930be21e0962aca15fce3e345da23debe4d6d92589928b09d2e769ac&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">ZESS Axio Observer3\u5012\u7f6e\u8367\u5149\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244252&amp;idx=1&amp;sn=0ac461362a91fa5205f559c5199a95c2&amp;chksm=8d748fddba0306cb105aea2a797a676fd3b9d54955ea9a5fb0676b052a90ef121543e7c840c4&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5982\u4f55\u4f7f\u7528ImageJ\u8fdb\u884c\u7ec6\u80de\u8367\u5149\u5b9a\u91cf<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244231&amp;idx=1&amp;sn=ed16d5ceefbca27277c98714731bb110&amp;chksm=8d748fc6ba0306d06624388772e689e81cc362698ef1096324683f46d7761c20de6d827fbdaa&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5982\u4f55\u4f7f\u7528Scrivener\u8fdb\u884c\u79d1\u6280\u8bba\u6587\u5199\u4f5c<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244183&amp;idx=1&amp;sn=aa2a848ab67d620f93862060b9955562&amp;chksm=8d749016ba031900d1c894b33982017d26a937119e20a96ff078189dec736f2b97e1059f22fe&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">Mendeley-\u6700\u597d\u7528\u7684\u6587\u732e\u9605\u8bfb\u7ba1\u7406\u8f6f\u4ef6\uff0c\u6ca1\u6709\u4e4b\u4e00<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244176&amp;idx=1&amp;sn=7f10fabdcf7f0d950a46240ec5fe15fb&amp;chksm=8d749011ba031907790577f28948aed880b0363c1347a4277d1c18fa771defb097ef9edb188f&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5982\u4f55\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u7684\u6742\u5fd7\u8fdb\u884c\u6295\u7a3f\uff1f<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244088&amp;idx=1&amp;sn=21d68a70f7bca71bfdde72c0d67f2a98&amp;chksm=8d7490b9ba0319af09932fbe11d466d7c89a0b0a075a6452872b5de237d1bc7b1ecaae24dc81&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244084&amp;idx=1&amp;sn=b88786b622f65d63e362f4c5c77bbeaf&amp;chksm=8d7490b5ba0319a34e65c5d39d2bffa07bf8950cb53409465a4889520feceed2f70519d6f84e&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244079&amp;idx=1&amp;sn=7b1487d81a45eec42e9d06c31ee0d24b&amp;chksm=8d7490aeba0319b88635d82077a37c473cf27f9877a4fb7928cfbb26169701804b657cae179f&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5982\u4f55\u6d4b\u91cfWestern Blot\u6761\u5e26\u7070\u5ea6\u503c\uff1f(GelPro\u8f6f\u4ef6\u4f7f\u7528\u65b9\u6cd5)<\/span><\/a><\/p>\n<p style=\"max-width: 100%; min-height: 1em; font-family: -apple-system-font, BlinkMacSystemFont, 'Helvetica Neue', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; box-sizing: border-box !important; word-wrap: break-word !important;\"><a style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0); cursor: pointer; max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important;\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244074&amp;idx=1&amp;sn=f5cbff4aabcf36dce3b6429e52b77305&amp;chksm=8d7490abba0319bd2818ce0a5f6775afd2b2cac8d959ce73bf8040165e5e02b46299438e6e53&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener\" data-itemshowtype=\"0\" data-linktype=\"2\"><span style=\"max-width: 100%; font-size: 16px; box-sizing: border-box !important; word-wrap: break-word !important;\">\u5b9e\u9a8c\u4e2d\u5982\u4f55\u6311\u9009\u5230\u4e00\u652f\u597d\u7528\u7684\u6297\u4f53\uff1f<\/span><\/a><\/p>\n<p style=\"margin: 0px; padding: 0px; text-align: left; color: #333333; text-indent: 2em; clear: both; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word; background-color: #ffffff;\">\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-indent: 32px; text-align: left;\"><span style=\"color: #000000; font-family: \u5b8b\u4f53;\"><span style=\"font-size: 16px; background-color: #ffffff;\">\u00a0<\/span><\/span><\/section>\n<p style=\"max-width: 100%; min-height: 1em; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; color: #000000; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: medium; text-align: center; line-height: 2em; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\"><span style=\"max-width: 100%; font-size: 12px; color: #595757; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\">\u2014 THE \u00a0END \u2014<\/span><\/p>\n<p style=\"max-width: 100%; min-height: 1em; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; color: #000000; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: medium; text-align: center; line-height: 2em; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%; min-height: 1em; letter-spacing: 0.544px; white-space: normal; color: #000000; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px; background-color: #ffffff; text-align: center; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\"><img decoding=\"async\" class=\"rich_pages\" style=\"box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important; visibility: visible !important; width: 155px !important;\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-02b1fa2647f727640451312635548126.jpeg\" data-ratio=\"1\" data-type=\"jpeg\" data-w=\"258\" data-s=\"300,640\" data-cropsely2=\"155\" data-cropsely1=\"0\" data-cropselx2=\"154\" data-cropselx1=\"0\" \/><\/p>\n<p style=\"max-width: 100%; min-height: 1em; letter-spacing: 0.544px; white-space: normal; color: #000000; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 14px; background-color: #ffffff; text-align: center; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\"><span style=\"max-width: 100%; font-size: 12px; color: #888888; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\">\u5173\u6ce8\u672c\u53f7\u56de\u590d201119\u5373\u53ef\u83b7\u53d6\u539f\u6587~<\/span><\/p>\n<p style=\"text-align: center; color: #554327; clear: both; box-sizing: border-box;\">\n<p style=\"text-align: center; color: #554327; box-sizing: border-box;\">\n<section style=\"margin-right: 8px; margin-left: 8px; max-width: 100%; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; color: #000000; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 16px; widows: 1; line-height: 2em; text-align: right; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\"><span style=\"max-width: 100%; font-size: 15px; background-color: #f9eda6; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\">\u70b9\u4eae\u201c\u5728\u770b\u201d<\/span><\/section>\n<section style=\"margin-right: 8px; margin-left: 8px; max-width: 100%; letter-spacing: 0.544px; white-space: normal; background-color: #ffffff; color: #000000; font-family: \u5fae\u8f6f\u96c5\u9ed1; font-size: 16px; widows: 1; line-height: 2em; text-align: right; box-sizing: border-box !important; overflow-wrap: break-word !important;\"><span style=\"max-width: 100%; font-size: 15px; background-color: #f9eda6; box-sizing: border-box !important; word-wrap: break-word !important; overflow-wrap: break-word !important;\">\u8ba9\u66f4\u591a\u4eba\u770b\u5230\uff01<\/span><\/section>\n<blockquote><p>\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\u5fae\u79d1\u4eab \uff0c\u4f5c\u8005\u592a\u9633\u5473\u7684\u98ce<\/p><\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 \u5bfc\u8bfb \u9752\u84bf\u7d20\u662f\u8457\u540d\u7684\u6297\u759f\u836f\u7269\uff0c\u8fd1\u671f\u7684\u5927\u91cf\u7814\u7a76\u8bc1\u660e\u4e86\u9752\u84bf\u7d20\u53ca\u5176\u884d\u751f\u7269\u8fd8\u5177\u5907\u6297\u5bc4\u751f\u866b\u3001\u6297\u80bf\u7624\u548c\u6291\u5236\u80a5\u80d6\u7684\u6f5c\u529b\u3002\u8fd9\u7bc7\u6587\u7ae0\u7740\u91cd\u4ecb\u7ecd\u4e86\u9752\u84bf\u7d20\u7684\u6297\u80a5\u80d6\u6f5c\u529b\uff0c\u5e76\u8ba4\u4e3a\u9752\u84bf\u7d20\u53ef\u4ee5\u901a\u8fc7\u8c03\u8282\u514d\u75ab\u7cfb\u7edf&hellip;<\/p>\n","protected":false},"author":1,"featured_media":3279,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[57],"tags":[],"_links":{"self":[{"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/3285"}],"collection":[{"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/comments?post=3285"}],"version-history":[{"count":1,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/3285\/revisions"}],"predecessor-version":[{"id":4323,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/3285\/revisions\/4323"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/media\/3279"}],"wp:attachment":[{"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/media?parent=3285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/categories?post=3285"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/dh.oncolab.cn\/index.php\/wp-json\/wp\/v2\/tags?post=3285"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}