{"id":3301,"date":"2020-11-16T17:25:20","date_gmt":"2020-11-16T09:25:20","guid":{"rendered":"http:\/\/dh.oncolab.cn\/index.php\/2020\/11\/16\/%e7%99%8c%e7%bb%86%e8%83%9e%e4%bb%a3%e8%b0%a2%e9%87%8d%e7%bc%96%e7%a8%8b%ef%bc%9a%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e5%8f%8d%e5%ba%94%e7%9a%84%e5%85%b3%e9%94%ae\/"},"modified":"2022-05-01T22:19:41","modified_gmt":"2022-05-01T14:19:41","slug":"%e7%99%8c%e7%bb%86%e8%83%9e%e4%bb%a3%e8%b0%a2%e9%87%8d%e7%bc%96%e7%a8%8b%ef%bc%9a%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e5%8f%8d%e5%ba%94%e7%9a%84%e5%85%b3%e9%94%ae","status":"publish","type":"post","link":"http:\/\/dh.oncolab.cn\/index.php\/2020\/11\/16\/%e7%99%8c%e7%bb%86%e8%83%9e%e4%bb%a3%e8%b0%a2%e9%87%8d%e7%bc%96%e7%a8%8b%ef%bc%9a%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e5%8f%8d%e5%ba%94%e7%9a%84%e5%85%b3%e9%94%ae\/","title":{"rendered":"\u764c\u7ec6\u80de\u4ee3\u8c22\u91cd\u7f16\u7a0b\uff1a\u514d\u75ab\u6cbb\u7597\u53cd\u5e94\u7684\u5173\u952e"},"content":{"rendered":"
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\u901a\u8fc7\u9776\u5411\u80bf\u7624\u5fae\u73af\u5883\u4ee5\u523a\u6fc0\u6297\u80bf\u7624\u514d\u75ab\u529b\uff0c\u514d\u75ab\u7597\u6cd5\u5f7b\u5e95\u6539\u53d8\u4e86\u764c\u75c7\u6cbb\u7597\u65b9\u6cd5\u3002<\/span>\u7136\u800c\uff0c\u8bb8\u591a\u60a3\u8005\u5728\u6700\u521d\u63a5\u53d7\u6cbb\u7597\u7684\u65f6\u5019\u6ca1\u6709\u6548\u679c\u6216\u540e\u671f\u53d1\u5c55\u4e3a\u7ee7\u53d1\u6027\u8010\u836f\u3002<\/span>\u57fa\u4e8e\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u6709\u9650\u7684\u8d44\u6e90\u4ee5\u53ca\u80bf\u7624\u4e0e\u514d\u75ab\u7ec6\u80de\u4e4b\u95f4\u7684\u7ade\u4e89\uff0c\u5927\u91cf\u7814\u7a76\u8868\u660e\u9776\u5411\u4ee3\u8c22\u53ef\u4ee5\u5e2e\u52a9\u8c03\u8282\u6297\u80bf\u7624\u514d\u75ab\u529b\u3002<\/span>\u4f46\u662f\uff0c\u5728\u6240\u6709\u4e0d\u540c\u7684\u6f5c\u5728\u53ef\u9776\u5411\u4ee3\u8c22\u9014\u5f84\u4e2d\u5c1a\u4e0d\u6e05\u695a\u54ea\u4e00\u79cd\u9014\u5f84\u66f4\u6709\u53ef\u80fd\u514b\u670d\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7684\u8010\u836f\u6027\u3002<\/span>\u5728\u8fd9\u91cc\uff0c\u4f5c\u8005\u63a2\u8ba8\u4e86\u764c\u7ec6\u80de\u4e2d\u4ee3\u8c22\u91cd\u7f16\u7a0b\u53ef\u80fd\u4f1a\u6291\u5236\u6297\u80bf\u7624\u514d\u75ab\uff0c\u4ee5\u53ca\u53ef\u7528\u4e8e\u4fc3\u8fdb\u6297\u80bf\u7624\u53cd\u5e94\u7684\u7b56\u7565\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8bba\u6587ID<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u539f\u540d\uff1a<\/span><\/strong><\/span>Cancer cell metabolic reprogramming: a keystone for theresponse to immunotherapy<\/span><\/section>\n
\u8bd1\u540d\uff1a<\/span><\/strong><\/span>\u764c\u7ec6\u80de\u4ee3\u8c22\u91cd\u7f16\u7a0b:\u514d\u75ab\u6cbb\u7597\u53cd\u5e94\u7684\u5173\u952e<\/span><\/section>\n
\u671f\u520a\uff1a<\/span><\/strong><\/span>Cell death & disease<\/span><\/section>\n
IF\uff1a<\/strong><\/span>6.304<\/span>
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\u53d1\u8868\u65f6\u95f4\uff1a<\/span><\/strong><\/span>2020.11<\/span><\/section>\n
\u901a\u8baf\u4f5c\u8005\uff1a<\/span><\/strong><\/span>St\u00e9phane Rocchi<\/span>\uff1b<\/span><\/span><\/section>\n
\u901a\u8baf\u4f5c\u8005\u5355\u4f4d\uff1a<\/strong><\/span>\u6cd5\u56fd\u851a\u84dd\u6d77\u5cb8\u5927\u5b66<\/span><\/section>\n
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\u5185\u5bb9<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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1.\u00a0\u80bf\u7624\u7ec6\u80de\u997f\u6b7bT\u7ec6\u80de\u4ee5\u963b\u6b62\u6297\u80bf\u7624\u514d\u75ab<\/span><\/strong><\/p>\n

\u00a0<\/span><\/strong><\/p>\n

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<\/p>\n

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\u00a0<\/span><\/strong><\/p>\n

2.\u00a0\u80bf\u7624\u7ec6\u80de\u4ee3\u8c22\u521b\u9020\u4e86\u4e00\u4e2a\u6076\u6027\u80bf\u7624\u5fae\u73af\u5883<\/span><\/strong><\/p>\n

\u00a0<\/span><\/strong><\/p>\n

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\u603b\u4e4b\uff0c\u9664\u4e86\u80bf\u7624\u7ec6\u80de\u7684\u76f4\u63a5\u9965\u997f\u6548\u5e94\uff0c\u80bf\u7624\u7ec6\u80de\u8fd8\u53ef\u4ee5\u5229\u7528\u7cd6\u9175\u89e3\u548c\u76f8\u5173\u8fc7\u7a0b\u5f62\u6210\u80bf\u7624\u5fae\u73af\u5883\u4ee5\u9003\u907f\u6297\u80bf\u7624\u514d\u75ab\uff0c\u8fdb\u800c\u7ee7\u7eed\u589e\u6b96(\u56fe2)\u3002<\/span><\/section>\n

<\/p>\n

\u56fe2\u00a0 \u80bf\u7624\u7ec6\u80de\u7cd6\u9175\u89e3\u5f62\u6210\u4e00\u4e2a\u9178\u6027\u7684\u5fae\u73af\u5883<\/span><\/strong><\/p>\n

\u00a0<\/span><\/strong><\/p>\n

3.\u00a0\u9776\u5411\u80bf\u7624\u7ec6\u80de\u4ee3\u8c22\u63d0\u9ad8\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u6ede\u6548\u7387<\/span><\/strong><\/p>\n

\u00a0<\/span><\/strong><\/p>\n

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<\/p>\n

\u56fe3\u00a0\u764c\u7ec6\u80de\u4e2d\u589e\u52a0\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u6ede\u6548\u7387\u7684\u6f5c\u5728\u53ef\u884c\u9014\u5f84<\/span><\/strong><\/p>\n

\u00a0<\/span><\/strong><\/p>\n

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\u00a0<\/span><\/strong><\/p>\n

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\u5173\u4e8e\u8c37\u6c28\u9170\u80fa\u4ee3\u8c22\u7684\u9776\u5411\u6cbb\u7597\uff0c\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u4e00\u9879\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6d4b\u8bd5\u8c37\u6c28\u9170\u80fa\u9176(GLS)\u5bf9\u80bf\u7624\u7684\u6291\u5236\u4f5c\u7528\u3002GLS\u662f\u8c37\u6c28\u9170\u80fa\u6c34\u89e3\u7684\u7b2c\u4e00\u79cd\u9176\uff0c\u7528\u4e8e\u8054\u5408\u5316\u7597\u52a0\u6297PD1\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002\u6b64\u5916\uff0c\u8003\u8651\u5230\u8c37\u6c28\u9170\u80fa\u62ee\u6297\u5242DON\u6297\u80bf\u7624\u53d6\u5f97\u7684\u4ee4\u4eba\u632f\u594b\u7684\u7ed3\u679c\uff0c\u5bf9\u8be5\u6cbb\u7597\u7b56\u7565\u7684\u8fdb\u884c\u4e34\u5e8a\u8bc4\u4f30\u662f\u5fc5\u8981\u7684\u3002<\/span><\/section>\n
\u6700\u540e\uff0c\u4f20\u7edf\u7684\u6297\u7cd6\u5c3f\u75c5\u836f\u7269\u4e8c\u7532\u53cc\u80cd\u4e5f\u5728\u4e0e\u514d\u75ab\u7597\u6cd5\u7684\u8054\u5408\u8bd5\u9a8c\u4e2d\u627e\u5230\u4e86\u7b2c\u4e8c\u4e2a\u201c\u9752\u6625\u201d\u3002\u6b63\u5982\u4e4b\u524d\u5728\u4f53\u5916\u548c\u4f53\u5185\u6570\u636e\u4e2d\u770b\u5230\u7684\uff0c\u9776\u5411AMPK\u53ef\u80fd\u662f\u4e00\u4e2a\u6709\u7528\u7684\u7b56\u7565\uff0c\u7528\u4ee5\u63d0\u9ad8\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7684\u6548\u7387\u3002\u4e8c\u7532\u53cc\u80cd\u5728\u5168\u7403\u8303\u56f4\u5185\u88ab\u7528\u4e8e\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u60a3\u8005\u8d85\u8fc71.2\u4ebf\u4eba\uff0c\u5bf9\u4e8c\u7532\u53cc\u80cd\u4e0d\u826f\u53cd\u5e94\u7684\u5e7f\u6cdb\u4e86\u89e3\u53ef\u80fd\u4f7f\u5176\u4e0e\u514d\u75ab\u7597\u6cd5\u7684\u8054\u5408\u66f4\u5b89\u5168\u3002\u8003\u8651\u5230\u4f7f\u7528\u4e8c\u7532\u53cc\u80cd\u6cbb\u7597\u7684\u60a3\u8005\u53d1\u751f\u764c\u75c7\u7684\u98ce\u9669\u8f83\u4f4e\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7ed3\u679c\u5c06\u662f\u6709\u7528\u7684(\u88681)\u3002<\/span><\/section>\n

\u8868\u4e00\u00a0 \u76ee\u524d\u6b63\u5728\u8fdb\u884c\u7684\u7ed3\u5408\u9776\u5411\u7ec6\u80de\u4ee3\u8c22\u836f\u7269\u548c\u514d\u75ab\u6cbb\u7597\u7b56\u7565\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5217\u8868<\/span><\/strong><\/p>\n

<\/p>\n

\n

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\u7ed3\u8bba<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u00a0<\/span><\/section>\n

\u5f80\u671f\u6587\u7ae0\u63a8\u8350<\/strong><\/span><\/p>\n

GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n

BD LSR Fortessa\u6d41\u5f0f-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n

BD Accuri C5\u6d41\u5f0f\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n

BD FACSJAZZ\u6d41\u5f0f\u7ec6\u80de\u5206\u9009\u4eea\u57fa\u672c\u53c2\u6570\u53ca\u5e94\u7528\u7b80\u4ecb<\/span><\/a><\/p>\n

BD Accuri C5\u6d41\u5f0f\u7ec6\u80de\u4eea\u4f7f\u7528\u89c4\u8303\u53ca\u64cd\u4f5c\u6d41\u7a0b<\/span><\/a><\/p>\n

\u514d\u75ab\u8367\u5149\u5b9e\u9a8c-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n

WB\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n

Annexin V\/PI\u67d3\u8272\u68c0\u6d4b\u7ec6\u80de\u51cb\u4ea1-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n

\u8521\u53f8LSM800\u6fc0\u5149\u5171\u805a\u7126\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n

ZESS Axio Observer3\u5012\u7f6e\u8367\u5149\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/p>\n

\u5982\u4f55\u4f7f\u7528ImageJ\u8fdb\u884c\u7ec6\u80de\u8367\u5149\u5b9a\u91cf<\/span><\/a><\/p>\n

\u5982\u4f55\u4f7f\u7528Scrivener\u8fdb\u884c\u79d1\u6280\u8bba\u6587\u5199\u4f5c<\/span><\/a><\/p>\n

Mendeley-\u6700\u597d\u7528\u7684\u6587\u732e\u9605\u8bfb\u7ba1\u7406\u8f6f\u4ef6\uff0c\u6ca1\u6709\u4e4b\u4e00<\/span><\/a><\/p>\n

\u5982\u4f55\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u7684\u6742\u5fd7\u8fdb\u884c\u6295\u7a3f\uff1f<\/span><\/a><\/p>\n

PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/span><\/a><\/p>\n

\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/span><\/a><\/p>\n

\u5982\u4f55\u6d4b\u91cfWestern Blot\u6761\u5e26\u7070\u5ea6\u503c\uff1f(GelPro\u8f6f\u4ef6\u4f7f\u7528\u65b9\u6cd5)<\/span><\/a><\/p>\n

\u5b9e\u9a8c\u4e2d\u5982\u4f55\u6311\u9009\u5230\u4e00\u652f\u597d\u7528\u7684\u6297\u4f53\uff1f<\/span><\/a><\/p>\n

\n

\u2014 THE \u00a0END \u2014<\/span><\/p>\n

\n

<\/p>\n

\u5173\u6ce8\u672c\u53f7\u56de\u590d201116\u5373\u53ef\u83b7\u53d6pdf\u539f\u6587~<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u70b9\u4eae\u201c\u5728\u770b\u201d<\/span><\/section>\n
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