{"id":3386,"date":"2021-01-05T16:49:33","date_gmt":"2021-01-05T08:49:33","guid":{"rendered":"http:\/\/dh.oncolab.cn\/index.php\/2021\/01\/05\/%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac3%e7%ab%a0%ef%bc%9a%e6%8a%97%e5%8e%9f%e8%af%86%e5%88%ab\/"},"modified":"2021-01-05T16:49:33","modified_gmt":"2021-01-05T08:49:33","slug":"%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac3%e7%ab%a0%ef%bc%9a%e6%8a%97%e5%8e%9f%e8%af%86%e5%88%ab","status":"publish","type":"post","link":"http:\/\/dh.oncolab.cn\/index.php\/2021\/01\/05\/%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac3%e7%ab%a0%ef%bc%9a%e6%8a%97%e5%8e%9f%e8%af%86%e5%88%ab\/","title":{"rendered":"\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c3\u7ae0\uff1a\u6297\u539f\u8bc6\u522b"},"content":{"rendered":"<div class='wxsyncmain'>\n<section style=\"box-sizing: border-box;font-size: 16px;text-align: left;\">\n<section style=\"box-sizing: border-box;font-size: 16px;\">\n<section style=\"text-align: center;margin: 10px 0% 15px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img decoding=\"async\" data-ratio=\"0.6076618\"  data-type=\"jpeg\" data-w=\"757\" style=\"vertical-align: middle;box-sizing: border-box;\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-b0fdb008b2baef5029679d07cdf9928f.jpeg\"  \/><\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"display: flex;flex-flow: row nowrap;margin: 20px 0% 10px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;align-self: center;background-color: rgb(49, 116, 161);flex: 0 0 auto;height: auto;border-width: 0px;line-height: 1.4;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;border-style: none;border-width: 0px;border-radius: 0px;border-color: rgb(49, 116, 161) rgb(49, 116, 161) rgb(49, 116, 161) rgb(0, 137, 123);flex: 100 100 0%;height: auto;box-sizing: border-box;\">\n<section style=\"padding-right: 10px;padding-left: 10px;line-height: 2;letter-spacing: 0px;color: rgb(0, 0, 0);font-size: 18px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5bfc \u8bfb<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5982\u7b2c1\u7ae0\u548c\u7b2c2\u7ae0\u6240\u8ff0\uff0c\u4eba\u7c7b\u8bc6\u522b\u5916\u6765\uff08\u975e\u81ea\u8eab\uff09\u7269\u8d28\u4e3b\u8981\u6709\u4e24\u4e2a\u7cfb\u7edf\uff1a\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u548c\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u7684\u7279\u5f81\u662f\u5b58\u5728\u541e\u566c\u7ec6\u80de\u548c\u8840\u6db2\u86cb\u767d\uff0c\u5b83\u4eec\u5229\u7528\u6a21\u5f0f\u8bc6\u522b\u5206\u5b50\u8bc6\u522b\u5165\u4fb5\u7684\u5fae\u751f\u7269\uff0c\u5982\uff1a\u7518\u9732\u805a\u7cd6\u7ed3\u5408\u51dd\u96c6\u7d20(MBL)\u548ctoll\u6837\u53d7\u4f53(TLRs)\u5c31\u662f\u5e38\u89c1\u7684\u6a21\u5f0f\u8bc6\u522b\u5206\u5b50\u3002\u5b83\u4eec\u80fd\u8bc6\u522b\u5e76\u7ed3\u5408\u5b58\u5728\u4e8e\u5fae\u751f\u7269\u800c\u975e\u5bbf\u4e3b\u7ec6\u80de\u4e2d\u7684\u5404\u79cd\u5206\u5b50\u3002MBL\u53ef\u4ee5\u5c06\u7518\u9732\u805a\u7cd6\u7ed3\u5408\u5728\u7ec6\u83cc\u3001\u75c5\u6bd2\u548c\u771f\u83cc\u7684\u8868\u9762\u3002\u7518\u9732\u805a\u7cd6\u4e0d\u5b58\u5728\u4e8e\u5065\u5eb7\u5bbf\u4e3b\u7ec6\u80de\u7684\u8868\u9762\uff0c\u4f46\u5b58\u5728\u4e8e\u53d7\u635f\u7ec6\u80de\u7684\u8868\u9762\u3002\u56e0\u6b64\uff0cMBL\u53ef\u4ee5\u8bc6\u522b\u7ed3\u5408\u5fae\u751f\u7269\u4ee5\u53ca\u53d7\u635f\u7684\u5bbf\u4e3b\u7ec6\u80de\uff0c\u4f46\u4e0d\u80fd\u8bc6\u522b\u6b63\u5e38\u7ec6\u80de\u3002\u867d\u7136MBL\u80fd\u591f\u533a\u5206\u5065\u5eb7\u548c\u75be\u75c5\uff0c\u4f46\u5b83\u88ab\u63cf\u8ff0\u4e3a\u201c\u975e\u7279\u5f02\u6027\u201d\uff0c\u56e0\u4e3a\u5b83\u4e0d\u80fd\u533a\u5206\u7ec6\u83cc\u548c\u75c5\u6bd2\uff0c\u4e5f\u4e0d\u80fd\u533a\u5206\u4e0d\u540c\u7c7b\u578b\u7684\u7ec6\u83cc\u3002\u8fd9\u79cd\u7279\u5f02\u6027\u7684\u7f3a\u4e4f\u662f\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u6a21\u5f0f\u8bc6\u522b\u5206\u5b50\u7684\u5173\u952e\u7279\u5f81\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u4f9d\u8d56\u4e8e\u4e00\u4e9b\u9884\u5148\u5b58\u5728\u7684\u5206\u5b50\u548c\u7ec6\u80de\u53bb\u975e\u7279\u5f02\u6027\u5730\u653b\u51fb\u5165\u4fb5\u8005;\u8fd9\u4e2a\u7cfb\u7edf\u53ef\u4ee5\u5f88\u597d\u5730\u4fdd\u62a4\u6211\u4eec\u514d\u53d7\u5404\u79cd\u611f\u67d3\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u5148\u5929\u7cfb\u7edf\u901a\u8fc7\u6e05\u9664\u611f\u67d3\u6e90\u6765\u9632\u6b62\u611f\u67d3\u3002\u7136\u800c\uff0c\u5b83\u4e0d\u80fd\u5bf9\u5fae\u751f\u7269\u6216\u5176\u4ed6\u5f02\u7269(\u6297\u539f)\u505a\u51fa\u7279\u5f02\u6027\u53cd\u5e94\u3002\u5fae\u751f\u7269\u7684\u8fdb\u5316\u901f\u5ea6\u6bd4\u810a\u690e\u52a8\u7269\u5feb\u5f97\u591a\uff0c\u56e0\u6b64\u5b83\u4eec\u80fd\u591f\u901a\u8fc7\u6539\u53d8\u81ea\u8eab\u7ed3\u6784\u9003\u907f\u975e\u9002\u5e94\u6027\u9632\u5fa1\u7cfb\u7edf\u3002\u8fd9\u5c31\u662f\u810a\u690e\u52a8\u7269\u53d1\u5c55\u51fa\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u7684\u539f\u56e0\u4e4b\u4e00\uff0c\u5b83\u4f9d\u8d56\u4e8e\u57fa\u56e0\u91cd\u6392\u4ea7\u751f\u5927\u91cf\u9884\u5148\u5b58\u5728\u4e8e\u6dcb\u5df4\u7ec6\u80de\u4e0a\u7684\u53d7\u4f53\uff08\u5e93\uff09\uff0c\u8fd9\u4e9b\u53d7\u4f53\u57fa\u672c\u4e0a\u53ef\u4ee5\u8bc6\u522b\u4efb\u4f55\u6297\u539f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"display: flex;flex-flow: row nowrap;margin: 20px 0% 10px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;align-self: center;background-color: rgb(49, 116, 161);flex: 0 0 auto;height: auto;border-width: 0px;line-height: 1.4;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;border-style: none;border-width: 0px;border-radius: 0px;border-color: rgb(49, 116, 161) rgb(49, 116, 161) rgb(49, 116, 161) rgb(0, 137, 123);flex: 100 100 0%;height: auto;box-sizing: border-box;\">\n<section style=\"padding-right: 10px;padding-left: 10px;line-height: 2;letter-spacing: 0px;color: rgb(0, 0, 0);font-size: 18px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u6297\u539f\u8bc6\u522b\u5206\u5b50<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5728\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u4e2d\u6709\u4e09\u7ec4\u5206\u5b50\u4e13\u95e8\u8d1f\u8d23\u8bc6\u522b\u5916\u6765\u6297\u539f\u3002\u524d\u4e24\u7ec4\u662f\u5728B\u548cT\u7ec6\u80de\u4e0a\u53d1\u73b0\u7684\u4f4d\u4e8e\u7ec6\u80de\u8868\u9762\u7684\u53d7\u4f53\u3002B\u7ec6\u80de\u53d7\u4f53(BCR)\u662f\u4ece\u5206\u5316\u7684B\u7ec6\u80de(\u6d46\u7ec6\u80de)\u5206\u6ccc\u51fa\u6765\u7684\u4e00\u79cd\u53ef\u6eb6\u6027\u6297\u539f\u53d7\u4f53\uff0c\u79f0\u4e3a\u6297\u4f53\u3002\u7b2c\u4e09\u7ec4\u6297\u539f\u53d7\u4f53\u5728\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u4f53(MHC)\u4e2d\u8fdb\u884c\u7f16\u7801\u3002\u8fd9\u7ec4\u57fa\u56e0\u5728\u4eba\u7c7b\u88ab\u79f0\u4e3a\u4eba\u7c7b\u767d\u7ec6\u80de\u6297\u539f(HLA)\u3002MHC\u5206\u5b50\u7684\u529f\u80fd\u662f\u5c06\u6297\u539f\u80bd\u5448\u9012\u7ed9T\u7ec6\u80de\u3002T\u7ec6\u80de\u53d7\u4f53(TCR)\u3001BCR\u548cMHC\u5206\u5b50\u5177\u6709\u76f8\u4f3c\u7684\u7ed3\u6784\uff0c\u5b83\u4eec\u662f\u5177\u6709\u514d\u75ab\u7403\u86cb\u767d\u6298\u53e0\u7684\u86cb\u767d\u8d28\u5206\u5b50\u5bb6\u65cf\u7684\u4e00\u90e8\u5206;\u8fd9\u4e2a\u5bb6\u65cf\u88ab\u79f0\u4e3a\u514d\u75ab\u7403\u86cb\u767d\u8d85\u5bb6\u65cf(\u89c1\u7b2c9\u7ae0)\u3002<span style=\"color: rgb(217, 33, 66);\">Fig3.1<\/span>\u603b\u7ed3\u4e86\u4e09\u79cd\u7c7b\u578b\u7684\u6297\u539f\u53d7\u4f53\u7684\u4e0d\u540c\u4e4b\u5904\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-bottom: 0px solid rgb(62, 62, 62);border-bottom-right-radius: 0px;width: 100%;height: auto;box-sizing: border-box;\"><img decoding=\"async\" data-ratio=\"0.8834951\"  data-type=\"jpeg\" data-w=\"618\" style=\"vertical-align: middle;width: 100%;box-sizing: border-box;\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-b1a5b9dd9cfa93c62d50fdb30aec98e8.jpeg\"  \/><\/section>\n<\/section>\n<section style=\"text-align: right;justify-content: flex-end;margin-right: 0%;margin-bottom: 10px;margin-left: 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: 30px;border-left: 2px solid rgb(113, 178, 198);border-bottom-left-radius: 0px;border-bottom: 2px solid rgb(113, 178, 198);border-bottom-right-radius: 0px;height: auto;line-height: 1;box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: 90%;height: auto;padding-left: 8px;box-sizing: border-box;\">\n<section style=\"text-align: justify;color: rgb(106, 106, 106);font-size: 15px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"color: rgb(203, 47, 21);box-sizing: border-box;\">Fig 3.1&nbsp;<\/span>B\u7ec6\u80de\u53d7\u4f53\u3001T\u7ec6\u80de\u53d7\u4f53\u548c\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269(MHC)\u5206\u5b50\u90fd\u662f\u514d\u75ab\u7403\u86cb\u767d\u8d85\u5bb6\u65cf\u7684\u6210\u5458\uff0c\u5177\u6709\u76f8\u4f3c\u7684\u7ed3\u6784\u3002\u8bf7\u6ce8\u610f\u5b83\u4eec\u7684\u529f\u80fd\u6709\u4f55\u4e0d\u540c\u3002APC, \u6297\u539f\u63d0\u5448\u7ec6\u80de\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"display: flex;flex-flow: row nowrap;margin: 20px 0% 10px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;align-self: center;background-color: rgb(49, 116, 161);flex: 0 0 auto;height: auto;border-width: 0px;line-height: 1.4;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;border-style: none;border-width: 0px;border-radius: 0px;border-color: rgb(49, 116, 161) rgb(49, 116, 161) rgb(49, 116, 161) rgb(0, 137, 123);flex: 100 100 0%;height: auto;box-sizing: border-box;\">\n<section style=\"padding-right: 10px;padding-left: 10px;line-height: 2;letter-spacing: 0px;color: rgb(0, 0, 0);font-size: 18px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">B\u7ec6\u80de\u53d7\u4f53(BCR)\u548cT\u7ec6\u80de\u53d7\u4f53(TCR)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5982\u7b2c2\u7ae0\u6240\u8ff0\uff0c\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u7684\u6709\u6548\u8fd0\u884c\u4f9d\u8d56\u4e8e\u514b\u9686\u9009\u62e9\u3002\u6bcf\u4e2aB\u7ec6\u80de\u6216T\u7ec6\u80de\u5728\u5176\u7ec6\u80de\u8868\u9762\u8868\u8fbe\u4e00\u79cd\u72ec\u7279\u7684\u6297\u539f\u53d7\u4f53\u3002\u5728\u9047\u5230\u5916\u6765\u6297\u539f\u65f6\uff0c\u8868\u8fbe\u6700\u5339\u914d\u7684\u6297\u539f\u53d7\u4f53\u7684\u7ec6\u80de\u4f1a\u5206\u88c2\u5e76\u4ea7\u751f\u5177\u6709\u76f8\u540c\u53d7\u4f53\u7684\u5b50\u7ec6\u80de(\u514b\u9686)\u3002\u53d7\u4f53\u7684\u591a\u6837\u6027\u662f\u7531\u57fa\u56e0\u91cd\u6392\u4ea7\u751f\u7684(\u89c1\u7b2c6\u7ae0\u548c\u7b2c7\u7ae0)\uff0c\u8fd9\u4f7f\u5f97\u5927\u91cf\u7684\u53d7\u4f53\u53ef\u4ee5\u7531\u6570\u91cf\u6709\u9650\u7684\u57fa\u56e0\u7ec4\u6210\uff0c\u4ece\u800c\u63d0\u4f9b\u8bc6\u522b\u6297\u539f\u6240\u9700\u7684\u591a\u6837\u6027\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: 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style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5728\u514d\u75ab\u5e94\u7b54\u8fc7\u7a0b\u4e2d\uff0c\u7f16\u7801B\u7ec6\u80de\u6297\u539f\u53d7\u4f53\u7684\u57fa\u56e0\u4e5f\u4f1a\u7ecf\u5386\u4e00\u4e2a\u79f0\u4e3a\u8d85\u7a81\u53d8\u7684\u8fc7\u7a0b\uff0c\u4ee5\u4ea7\u751f\u66f4\u9002\u5408\u5916\u6765\u6297\u539f\u7684\u53d7\u4f53\u3002\u8fd9\u79cd\u7f16\u7801\u6297\u539f\u7ed3\u5408\u4f4d\u70b9\u7684\u5e8f\u5217\u7684\u5feb\u901f\u7a81\u53d8\u8fc7\u7a0b\u521b\u9020\u4e86\u66f4\u591a\u72ec\u7279\u7684\u53d7\u4f53\u548c\u66f4\u7279\u5f02\u3001\u66f4\u591a\u6837\u5316\u7684\u53d7\u4f53\u5e93\u3002\u9664\u4e86\u901a\u8fc7\u76f8\u4f3c\u7684\u9057\u4f20\u673a\u5236\u4ea7\u751f\u5916\uff0cB\u7ec6\u80de\u548cT\u7ec6\u80de\u7684\u6297\u539f\u53d7\u4f53\u5728\u5b83\u4eec\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u65b9\u9762\u4e5f\u662f\u76f8\u4f3c\u7684\u3002\u5b83\u4eec\u6709\u4e00\u79cd\u88ab\u79f0\u4e3a\u514d\u75ab\u7403\u86cb\u767d\u6298\u53e0\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u7279\u5f81\uff0c\u8fd9\u662f\u51e0\u4e2a\u53d7\u4f53\u5bb6\u65cf\u5e38\u89c1\u7684\u3002\u5728\u8fd9\u4e9b\u53d7\u4f53\u5bb6\u65cf\u4e2d\uff0c\u5305\u62ec\u514d\u75ab\u7ec6\u80de\u4e0a\u53d1\u73b0\u7684\u6297\u539f\u53d7\u4f53\uff0c\u5e73\u884c\u7684\u6c28\u57fa\u9178\u94fe\u90fd\u662f\u6298\u53e0\u6210\u4e00\u4e2a\u7d27\u51d1\u7684\u7403\u72b6\u7ed3\u6784\u57df\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"display: flex;flex-flow: row nowrap;margin: 20px 0% 10px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 15%;align-self: center;background-color: rgb(49, 116, 161);flex: 0 0 auto;height: auto;border-width: 0px;line-height: 1.4;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: auto;align-self: center;border-style: none;border-width: 0px;border-radius: 0px;border-color: rgb(49, 116, 161) rgb(49, 116, 161) rgb(49, 116, 161) rgb(0, 137, 123);flex: 100 100 0%;height: auto;box-sizing: border-box;\">\n<section style=\"padding-right: 10px;padding-left: 10px;line-height: 2;letter-spacing: 0px;color: rgb(0, 0, 0);font-size: 18px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269\u5206\u5b50(MHC)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">MHC\u6700\u521d\u56e0\u5176\u5728\u7ec4\u7ec7\u6392\u65a5(\u76f8\u5bb9\u6027)\u4e2d\u7684\u4f5c\u7528\u800c\u547d\u540d\uff0c\u662f\u7531MHC\u57fa\u56e0\u7f16\u7801\u7684\u7b2c\u4e09\u7c7b\u6297\u539f\u53d7\u4f53\u5206\u5b50\u3002\u4e3b\u8981\u6709\u4e24\u7c7b\uff0cI\u7c7bMHC\u5206\u5b50\u57fa\u672c\u4e0a\u5b58\u5728\u4e8e\u6240\u6709\u7ec6\u80de\u4e0a\uff0cII\u7c7bMHC\u5206\u5b50\u4e3b\u8981\u5b58\u5728\u4e8e\u6297\u539f\u63d0\u5448\u7ec6\u80de(B\u7ec6\u80de\u3001\u5de8\u566c\u7ec6\u80de\u548c\u6811\u7a81\u72b6\u7ec6\u80de)\u4e0a\u3002I\u7c7b\u548cII\u7c7bMHC\u5206\u5b50\u7684\u4e3b\u8981\u529f\u80fd\u5747\u662f\u5411T\u7ec6\u80de\u9012\u5448\u6297\u539f\u80bd\u3002\u6b64\u5916\uff0cMHC\u8fd8\u6709\u4e00\u4e2a\u4f5c\u7528\u662f\u8c03\u8282\u81ea\u7136\u6740\u4f24(NK)\u7ec6\u80de\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">MHC\u5206\u5b50\u7684\u7ed3\u6784\u5c06\u5728\u7b2c8\u7ae0\u8be6\u7ec6\u63cf\u8ff0\uff0c\u5b83\u4eec\u7684\u529f\u80fd\u5c06\u5728\u7b2c10\u7ae0\u63cf\u8ff0\u3002\u7b80\u800c\u8a00\u4e4b\uff0cTCR\u53ea\u6709\u5728\u4e0eMHC\u5206\u5b50\u5f62\u6210\u590d\u5408\u7269\u65f6\u624d\u80fd\u8bc6\u522b\u5916\u6765\u6297\u539f\u3002TCR\u4e0e\u5916\u6e90\u80bd\u548cMHC\u5206\u5b50\u4e0a\u7684\u6b8b\u57fa\u63a5\u89e6\uff0c\u8fd9\u662f\u4e00\u79cd\u4e0d\u540c\u4e8eB\u7ec6\u80de\u6297\u539f\u53d7\u4f53\u7684\u6297\u539f\u8bc6\u522b\uff0cB\u7ec6\u80de\u6297\u539f\u53d7\u4f53\u76f4\u63a5\u4e0e\u6297\u539f\u7ed3\u5408\u3002\u53cc\u91cd\u8bc6\u522b\u7684\u8981\u6c42\u5c06TCR\u5206\u5b50\u4e0eBCR\u5206\u5b50\u533a\u5206\u5f00\u6765\u3002MHC\u5206\u5b50\u7684\u751f\u7406\u529f\u80fd\u662f\u6355\u83b7\u5e76\u663e\u793a\u6765\u81ea\u7ec6\u80de\u76f8\u5173\u5fae\u751f\u7269(\u5982\u5bbf\u4e3b\u7ec6\u80de\u4e2d\u5236\u9020\u7684\u75c5\u6bd2\u86cb\u767d)\u7684\u6297\u539f\uff0c\u4ee5\u4f9bT\u7ec6\u80de\u8bc6\u522b\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;text-align: justify;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;width: 100%;border-width: 2px;border-style: dashed;border-color: rgb(192, 200, 209);padding: 10px;background-color: rgb(241, 248, 240);border-radius: 0.7em;box-sizing: border-box;\">\n<section style=\"color: rgb(0, 0, 0);box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u7f16\u7801MHC\u5206\u5b50\u7684\u57fa\u56e0\u662f\u6211\u4eec\u6240\u5df2\u77e5\u7684\u4eba\u7c7b\u57fa\u56e0\u7ec4\u4e2d\u53d8\u5f02\u6700\u5927\u7684\u57fa\u56e0\u3002\u5b83\u4eec\u88ab\u8ba4\u4e3a\u662f\u5e7f\u6cdb\u591a\u6001\u7684\uff0c\u8fd9\u610f\u5473\u7740\u540c\u4e00\u57fa\u56e0\u5b58\u5728\u591a\u4e2a\u7b49\u4f4d\u57fa\u56e0\u6216\u591a\u79cd\u5f62\u5f0f\u3002\u7136\u800c\uff0c\u5b83\u4eec\u7684\u591a\u6837\u6027\u5b58\u5728\u4e8e\u6574\u4e2a\u7fa4\u4f53\u4e2d\uff0c\u800c\u4e0d\u662f\u5b58\u5728\u4e8e\u4e2a\u4f53\u4e2d\u3002<span style=\"color: rgb(217, 33, 66);\">Fig3.2<\/span>\u6bd4\u8f83\u4e86MHC\u591a\u6837\u6027\u4e0e\u514d\u75ab\u7403\u86cb\u767d\u548cTCR\u591a\u6837\u6027\u3002\u6bcf\u4e2a\u4eba\u5927\u7ea6\u6709\u516d\u79cd\u4e0d\u540c\u7684I\u7c7b\u548cII\u7c7bMHC\u57fa\u56e0\u4ea7\u7269\u3002\u8003\u8651\u5230\u4ed6\u4eec\u7684\u7236\u6bcd\u53ef\u80fd\u6709\u5b8c\u5168\u4e0d\u540c\u7684HLA\u57fa\u56e0\uff0c\u5927\u591a\u6570\u4eba\u7684\u7ec6\u80de\u8868\u9762\u670912\u4e2a\u4e0d\u540c\u7684I\u7c7b\u548cII\u7c7bMHC\u5206\u5b50\u3002B\u7ec6\u80de\u6216T\u7ec6\u80de\u53d7\u4f53\u5728\u4e2a\u4f53\u7684\u6bcf\u4e2a\u6dcb\u5df4\u7ec6\u80de\u4e2d\u90fd\u662f\u4e0d\u540c\u7684\uff0c\u4f46\u6240\u6709\u7684MHC\u7b49\u4f4d\u57fa\u56e0\u5728\u4e2a\u4f53\u4e2d\u90fd\u662f\u76f8\u540c\u7684\uff0c\u4e2a\u4f53\u4e4b\u95f4\u662f\u4e0d\u540c\u7684\u3002\u56e0\u6b64\uff0c\u5728\u6574\u4e2a\u79cd\u7fa4\u4e2d\uff0c\u6709\u53ef\u80fd\u4e00\u4e9bMHC\u5206\u5b50\u53ef\u4ee5\u7ed3\u5408\u6765\u81ea\u7279\u5b9a\u5fae\u751f\u7269\u7684\u6297\u539f\u80bd\uff0c\u4e5f\u6709\u53ef\u80fd\u4efb\u4f55\u7ed9\u5b9a\u7684\u4e2a\u4f53\u90fd\u4e0d\u80fd\u7ed3\u5408\u6765\u81ea\u8be5\u5fae\u751f\u7269\u7684\u80bd\u3002\u8fd9\u610f\u5473\u7740\u7fa4\u4f53\u4e2d\u7684\u4e00\u4e9b\u4eba\u53ef\u80fd\u6bd4\u5176\u4ed6\u4eba\u66f4\u5bb9\u6613\u611f\u67d3\u67d0\u79cd\u7279\u5b9a\u5fae\u751f\u7269\u5f15\u8d77\u7684\u75be\u75c5\u3002\u4f8b\u5982\uff0c\u5982\u679c\u4f60\u7684MHC\u5206\u5b50\u7684\u7ed3\u6784\u4f7f\u4f60\u4e0d\u53ef\u80fd\u8bc6\u522b\u548c\u7ed3\u5408\u6765\u81ea\u7279\u5b9a\u75c5\u6bd2\u7684\u4efb\u4f55\u80bd\u6297\u539f\uff0c\u4f60\u5c31\u4e0d\u80fd\u6fc0\u6d3bT\u7ec6\u80de\u5bf9\u611f\u67d3\u8be5\u75c5\u6bd2\u7684\u7ec6\u80de\u53cd\u5e94\uff0c\u56e0\u6b64\uff0c\u4f60\u5c31\u4f1a\u5f88\u5bb9\u6613\u611f\u67d3\u8be5\u75c5\u6bd2\u5f15\u8d77\u7684\u75be\u75c5\u3002\u7136\u800c\uff0cMHC\u5206\u5b50\u4e2d\u591a\u80bd\u7ed3\u5408\u69fd\u7684\u5e7f\u6cdb\u7279\u5f02\u6027(\u5728\u7b2c8\u7ae0\u548c\u7b2c10\u7ae0\u4e2d\u63cf\u8ff0)\u4f7f\u5f97\u6765\u81ea\u67d0\u79cd\u7279\u5b9a\u5fae\u751f\u7269\u7684\u4efb\u4f55\u591a\u80bd\u90fd\u4e0d\u80fd\u7ed3\u5408\u67d0\u4e2a\u4eba\u7684MHC\u5206\u5b50\u7684\u53ef\u80fd\u6027\u6781\u5c0f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin-top: 10px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-bottom: 0px solid rgb(62, 62, 62);border-bottom-right-radius: 0px;width: 100%;height: auto;box-sizing: border-box;\"><img decoding=\"async\" data-ratio=\"1.0326679\"  data-type=\"jpeg\" data-w=\"551\" style=\"vertical-align: middle;width: 100%;box-sizing: border-box;\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-35ee722d71b7aaa9c176753de40c5a0b.jpeg\"  \/><\/section>\n<\/section>\n<section style=\"text-align: right;justify-content: flex-end;margin-right: 0%;margin-bottom: 10px;margin-left: 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"display: inline-block;vertical-align: top;width: 30px;border-left: 2px solid rgb(113, 178, 198);border-bottom-left-radius: 0px;border-bottom: 2px solid rgb(113, 178, 198);border-bottom-right-radius: 0px;height: auto;line-height: 1;box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: 90%;height: auto;padding-left: 8px;box-sizing: border-box;\">\n<section style=\"text-align: justify;color: rgb(106, 106, 106);font-size: 15px;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"color: rgb(203, 47, 21);box-sizing: border-box;\">Fig 3.2&nbsp;<\/span>\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269(MHC)\u4e0e\u514d\u75ab\u7403\u86cb\u767d(Ig)\u4ee5\u53caT\u7ec6\u80de\u53d7\u4f53(TCR)\u7684\u5dee\u5f02<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"transform-origin: center center;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"display: inline-block;width: 100%;vertical-align: top;background-color: rgb(214, 238, 214);padding: 15px;border-width: 0px;border-radius: 0px;border-style: none;border-color: rgb(62, 62, 62);box-sizing: border-box;\">\n<section style=\"margin-top: 3px;margin-right: 0%;margin-left: 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(0, 0, 0);font-size: 17px;letter-spacing: 1.8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">BOX 3.1 \u4eba\u7c7b\u767d\u7ec6\u80de\u6297\u539f\u591a\u6837\u6027\u7684\u4f18\u52bf<\/p>\n<\/section>\n<\/section>\n<section style=\"margin: 7px 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"border-top: 4px solid rgb(50, 116, 6);box-sizing: border-box;\">\n<section><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<section style=\"margin-top: 3px;border-top: 1px solid rgb(50, 116, 6);box-sizing: border-box;\">\n<section><svg viewbox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"margin-right: 0%;margin-left: 0%;box-sizing: border-box;\" powered-by=\"xiumi.us\">\n<section style=\"color: rgb(0, 0, 0);font-size: 15px;line-height: 1.8;letter-spacing: 1.8px;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;text-align: justify;\">\u6709\u4e9b\u57fa\u56e0\u591a\u6001\u6027\u6bd4\u611f\u67d3\u66f4\u5177\u4f18\u52bf\u3002\u6700\u5e7f\u4e3a\u4eba\u77e5\u7684\u4f8b\u5b50\u662f\u9570\u72b6\u7ec6\u80de\u7684\u7279\u6027\u548c\u5bf9\u759f\u75be\u7684\u4fdd\u62a4\u3002\u5177\u6709\u9570\u72b6\u7ec6\u80de\u7279\u5f81\u7684\u4eba\u7684\u57fa\u56e0\u662f\u8840\u7ea2\u86cb\u767d\u03b2-\u94fe\u5f02\u5e38\u7684\u6742\u5408\u5b50\u3002\u8fd9\u79cd\u5f02\u5e38\u57fa\u56e0\u7684\u7eaf\u5408\u5b50\u5bfc\u81f4\u4e25\u91cd\u7684\u9570\u72b6\u7ec6\u80de\u75be\u75c5\u548c\u8840\u6db2\u5b66\u95ee\u9898\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u5177\u6709\u9570\u72b6\u7ec6\u80de\u7279\u5f81\u7684\u6742\u5408\u5b50\u53ea\u6709\u8f7b\u5fae\u7684\u8840\u6db2\u5b66\u95ee\u9898\u3002\u6b64\u5916\uff0c\u5f02\u5e38\u57fa\u56e0\u7684\u6742\u5408\u6027\u4f7f\u7ea2\u7ec6\u80de\u5bf9\u759f\u75be\u7684\u5bc4\u751f\u5177\u6709\u62b5\u6297\u529b\u3002\u56e0\u6b64\uff0c\u9570\u72b6\u7ec6\u80de\u7684\u7279\u6027\u5c06\u4e25\u91cd\u759f\u75be\u7684\u98ce\u9669\u964d\u4f4e\u4e8690%\u3002\u759f\u75be\u4ecd\u7136\u662f\u4e16\u754c\u4e00\u4e9b\u5730\u533a\u4e00\u79cd\u7684\u91cd\u8981\u4f20\u67d3\u75c5\uff0c\u4f8b\u5982\u5728\u6492\u54c8\u62c9\u4ee5\u5357\u7684\u975e\u6d32\u3002\u8bb8\u591a\u975e\u6d32\u8840\u7edf\u7684\u4eba\u4ecd\u7136\u643a\u5e26\u7740\u4e0d\u6b63\u5e38\u7684\u8840\u7ea2\u86cb\u767d\u57fa\u56e0\uff0c\u800c\u8fd9\u5728\u5176\u4ed6\u79cd\u65cf\u4e2d\u5df2\u7ecf\u53d8\u5f97\u975e\u5e38\u7f55\u89c1\u3002\u759f\u75be\u548c\u9570\u72b6\u7ec6\u80de\u7279\u5f81\u4e4b\u95f4\u7684\u5173\u7cfb\u4fc3\u8fdb\u4e86\u4eba\u7c7b\u8fdb\u5316\uff0c\u662f\u75c5\u539f\u4f53\u4ecb\u5bfc\u7684\u9009\u62e9\u7684\u4e00\u4e2a\u4f8b\u5b50\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;text-align: justify;\">&nbsp; &nbsp; \u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269(MHC)\u57fa\u56e0\u7684\u8868\u73b0\u4e0d\u540c\uff0c\u4f46\u4ed6\u4eec\u7684\u5de8\u5927\u7684\u591a\u6837\u6027\u4e5f\u662f\u53d7\u5230\u75c5\u539f\u4f53\u9a71\u52a8\u7684\u3002\u4e0d\u540c\u7684MHC\u7b49\u4f4d\u57fa\u56e0\u5448\u9012\u6765\u81ea\u7279\u5b9a\u611f\u67d3\u7684\u6297\u539f\u7684\u80fd\u529b\u5404\u4e0d\u76f8\u540c\uff1b\u56e0\u6b64\uff0c\u7279\u5b9a\u7684MHC\u7b49\u4f4d\u57fa\u56e0\u53ef\u80fd\u4f7f\u53d7\u611f\u67d3\u7684\u4e2a\u4f53\u6216\u591a\u6216\u5c11\u5730\u503e\u5411\u4e8e\u6709\u5229\u7684\u75be\u75c5\u7ed3\u5c40\u3002\u8fd9\u5df2\u88ab\u8bc1\u660e\u9002\u7528\u4e8e\u827e\u6ecb\u75c5\u75c5\u6bd2\u548c\u4e59\u578b\u809d\u708e\u75c5\u6bd2(HBV)\u611f\u67d3\u3002\u75c5\u539f\u4f53\u4ecb\u5bfc\u7684MHC\u9009\u62e9\u4e2d\uff0c\u4e0d\u540c\u7684\u673a\u5236\u5982\u4e0b\uff1a<span style=\"letter-spacing: 1.8px;box-sizing: border-box;\">\u6742\u5408\u5b50\u4f18\u52bf\uff1a\u5982\u679c\u7fa4\u4f53\u4e2d\u7684\u4e2a\u4f53\u503e\u5411\u4e8eMHC\u7b49\u4f4d\u57fa\u56e0\u7684\u6742\u5408\u5b50\uff0c\u4ed6\u4eec\u66f4\u6709\u53ef\u80fd\u5177\u6709\u4fdd\u62a4\u6027\u7b49\u4f4d\u57fa\u56e0\u3002<\/span><span style=\"letter-spacing: 1.8px;box-sizing: border-box;\">\u7f55\u89c1\u7684\u7b49\u4f4d\u57fa\u56e0\u4f18\u52bf\uff1a\u4e00\u79cd\u65b0\u7684\u611f\u67d3\u53ef\u80fd\u8fdb\u5316\u5e76\u6210\u529f\uff0c\u56e0\u4e3a\u5b83\u907f\u5f00\u4e86\u4eba\u7fa4\u4e2d\u6d41\u884c\u7684MHC\u7b49\u4f4d\u57fa\u56e0\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u643a\u5e26\u7f55\u89c1MHC\u7b49\u4f4d\u57fa\u56e0\u7684\u4e2a\u4f53\u66f4\u6709\u53ef\u80fd\u5b58\u6d3b\u4e0b\u6765\u3002<\/span><span style=\"letter-spacing: 1.8px;\">\u8fd9\u4e24\u79cd\u6a21\u578b\u90fd\u652f\u6301MHC\u7b49\u4f4d<\/span><span style=\"letter-spacing: 1.8px;\">\u57fa\u56e0\u7684\u9057\u4f20\u591a\u6837\u6027\u3002<\/span><span style=\"letter-spacing: 1.8px;\">\u6362\u53e5\u8bdd\u8bf4\uff0c\u4e00\u4e2a\u7fa4\u4f53\u4e2d\u53ef\u7528\u7684MHC\u7b49\u4f4d\u57fa\u56e0\u8d8a\u591a\uff0c\u8be5\u7fa4\u4f53\u5728\u65b0\u611f\u67d3\u4e2d\u5b58\u6d3b\u7684\u53ef\u80fd\u6027\u5c31\u8d8a\u5927\u3002<\/span><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;text-align: justify;\">&nbsp; &nbsp; \u5c3d\u7ba1MHC\u591a\u6837\u6027\u964d\u4f4e\u4e86\u4eba\u7c7b\u79cd\u7fa4\u88ab\u65b0\u51fa\u73b0\u7684\u611f\u67d3\u6d88\u706d\u7684\u98ce\u9669\uff0c\u4f46\u5b83\u5728\u79fb\u690d\u4e2d\u9020\u6210\u4e86\u91cd\u5927\u95ee\u9898\u3002\u6b63\u5982\u4f60\u5c06\u5728\u7b2c34\u7ae0\u4e2d\u770b\u5230\u7684\uff0c\u6210\u529f\u7684\u79fb\u690d\u9700\u8981\u4f9b\u8005\u548c\u63a5\u53d7\u8005\u5c3d\u53ef\u80fd\u5177\u6709\u76f8\u4f3c\u7684MHC\u7b49\u4f4d\u57fa\u56e0\u3002\u7531\u4e8eMHC\u7684\u591a\u6837\u6027\uff0c\u5bf9\u4e8e\u4efb\u4f55\u53ef\u7528\u7684\u968f\u673a\u80be\u810f\uff0c\u4efb\u4f55\u60a3\u8005\u5728\u6240\u6709MHC\u7b49\u4f4d\u57fa\u56e0\u4e0a\u90fd\u53ea\u6709\u5341\u4e07\u5206\u4e4b\u4e00\u7684\u673a\u4f1a\u76f8\u540c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"text-align: center;margin: 10px 32px;box-sizing: border-box;\"><span style=\"color: rgb(0, 0, 0);font-size: 12px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;text-indent: 0em;\">\u672c\u6587\u7531Oncolab\u5b9e\u9a8c\u5ba4\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaImmunology for Medical Students\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span><br  \/><\/section>\n<\/section>\n<section style=\"margin-right: 48px;margin-left: 48px;white-space: normal;max-width: 100%;min-height: 1em;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(0, 0, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2014 THE &nbsp;END \u2014<\/span><\/p>\n<section style=\"white-space: normal;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6765\u6e90&nbsp;| Immunology for Medical Students<\/span><\/section>\n<section style=\"white-space: normal;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 12px;max-width: 100%;letter-spacing: 0.544px;\">\u7ffb\u8bd1&nbsp;|&nbsp;<\/span>\u9648\u79cb\u8c37&nbsp;\u7f57\u4f73\u4f73&nbsp;\u848b\u4fca\u535a<\/span><\/section>\n<section style=\"white-space: normal;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7f16\u8f91\u6392\u7248<span style=\"font-size: 12px;max-width: 100%;letter-spacing: 0.544px;\">&nbsp;|<\/span><span style=\"font-size: 12px;max-width: 100%;letter-spacing: 0.544px;\">&nbsp;\u90d1\u68a6\u6021<\/span><\/span><\/section>\n<section style=\"white-space: normal;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5ba1\u6838&nbsp;|&nbsp;&nbsp;\u738b\u5764 \u5b8b\u4e50<\/span><\/section>\n<section style=\"white-space: normal;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/section>\n<p style=\"margin-bottom: 10px;text-indent: 0em;white-space: normal;max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: left;line-height: normal;letter-spacing: 0.54px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0em;font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;letter-spacing: 0.544px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;font-family: Arial, sans-serif;letter-spacing: 2px;color: rgb(64, 118, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2589&nbsp;&nbsp;\u5f80\u671f\u7cbe\u5f69\u5185\u5bb9\u63a8\u8350<\/strong><\/strong><\/p>\n<p style=\"margin-bottom: 10px;text-indent: 0em;white-space: normal;max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: left;line-height: normal;letter-spacing: 0.54px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 14px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245349&amp;idx=1&amp;sn=a13e314b760a526949b1cee171307fbf&amp;chksm=8d748ba4ba0302b21ea74a8c046a5d11a9349e4a775a779d09a1556007633b65a87e4c3ea3df&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c2\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u57fa\u672c\u6982\u5ff5\u548c\u7ec4\u6210<\/a><\/span><br  \/><\/p>\n<p style=\"margin-bottom: 10px;text-indent: 0em;white-space: normal;max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: left;line-height: normal;letter-spacing: 0.54px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-size: 14px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245279&amp;idx=1&amp;sn=38ccf0ede5794a92636b3dc088897cff&amp;chksm=8d748bdeba0302c8c37fa7a7640dca9f9b100493a4e528788060cf671b881a783055513f1798&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener\">\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c1\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7b80\u4ecb<\/a><\/span><\/p>\n<p style=\"margin-bottom: 10px;text-indent: 0em;white-space: normal;max-width: 100%;min-height: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: left;line-height: normal;letter-spacing: 0.54px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245082&amp;idx=1&amp;sn=7cb0b8f302f6746066637f7abfc576ef&amp;chksm=8d748c9bba03058d81ec66f0da9a87ebbff4088e871524e32cf318c3dbe67fb1e1b2de6ad417&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"text-indent: 0em;letter-spacing: 0.544px;text-align: justify;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/p>\n<section mpa-from-tpl=\"t\" style=\"white-space: normal;max-width: 100%;box-sizing: border-box;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" powered-by=\"xiumi.us\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section mpa-from-tpl=\"t\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;text-indent: 2em;text-align: left;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456245126&amp;idx=1&amp;sn=539b872b0986afaf604a5864a2033596&amp;chksm=8d748c47ba0305514f8bc92890957ffdd81c38f8d84d659994f25b8787d63c52a222818fc061&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\">PD-1\/PD-L1\u963b\u65ad\u5242\u6cbb\u7597\u80bf\u7624\u7684\u7814\u7a76\u8fdb\u5c55\u4e0e\u9762\u4e34\u7684\u6311\u6218<\/a><\/span><\/section>\n<section style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244538&amp;idx=1&amp;sn=a341bcb7073f3fa61bfffcb3a35c556e&amp;chksm=8d748efbba0307ede3604f128d0aa2a9d3a53890374261817762dca4b61a69b08a95864b5451&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Immunity\uff1a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u5341\u5927\u6311\u6218<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;text-indent: 2em;letter-spacing: 0.544px;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244984&amp;idx=1&amp;sn=9203285637478abe17fea957bb4a4b3c&amp;chksm=8d748d39ba03042fceb79cdd77d520d07e613fc04f9be12fb7a759b7fb11b0581066a81689e0&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;text-indent: 2em;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\">BD LSR Fortessa\u6d41\u5f0f-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a><\/span><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244905&amp;idx=1&amp;sn=9e75242aa7a3bbc991e76d7987f0b503&amp;chksm=8d748d68ba03047e146a11c1337eb57a148665f60dc7c4bb429d3abe72b6241f430444142218&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\">\u8521\u53f8LSM800\u6fc0\u5149\u5171\u805a\u7126\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a><\/span><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244252&amp;idx=1&amp;sn=0ac461362a91fa5205f559c5199a95c2&amp;chksm=8d748fddba0306cb105aea2a797a676fd3b9d54955ea9a5fb0676b052a90ef121543e7c840c4&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5982\u4f55\u4f7f\u7528ImageJ\u8fdb\u884c\u7ec6\u80de\u8367\u5149\u5b9a\u91cf<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244231&amp;idx=1&amp;sn=ed16d5ceefbca27277c98714731bb110&amp;chksm=8d748fc6ba0306d06624388772e689e81cc362698ef1096324683f46d7761c20de6d827fbdaa&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5982\u4f55\u4f7f\u7528Scrivener\u8fdb\u884c\u79d1\u6280\u8bba\u6587\u5199\u4f5c<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244183&amp;idx=1&amp;sn=aa2a848ab67d620f93862060b9955562&amp;chksm=8d749016ba031900d1c894b33982017d26a937119e20a96ff078189dec736f2b97e1059f22fe&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Mendeley-\u6700\u597d\u7528\u7684\u6587\u732e\u9605\u8bfb\u7ba1\u7406\u8f6f\u4ef6\uff0c\u6ca1\u6709\u4e4b\u4e00<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244176&amp;idx=1&amp;sn=7f10fabdcf7f0d950a46240ec5fe15fb&amp;chksm=8d749011ba031907790577f28948aed880b0363c1347a4277d1c18fa771defb097ef9edb188f&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5982\u4f55\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u7684\u6742\u5fd7\u8fdb\u884c\u6295\u7a3f\uff1f<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244088&amp;idx=1&amp;sn=21d68a70f7bca71bfdde72c0d67f2a98&amp;chksm=8d7490b9ba0319af09932fbe11d466d7c89a0b0a075a6452872b5de237d1bc7b1ecaae24dc81&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244084&amp;idx=1&amp;sn=b88786b622f65d63e362f4c5c77bbeaf&amp;chksm=8d7490b5ba0319a34e65c5d39d2bffa07bf8950cb53409465a4889520feceed2f70519d6f84e&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244079&amp;idx=1&amp;sn=7b1487d81a45eec42e9d06c31ee0d24b&amp;chksm=8d7490aeba0319b88635d82077a37c473cf27f9877a4fb7928cfbb26169701804b657cae179f&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5982\u4f55\u6d4b\u91cfWestern Blot\u6761\u5e26\u7070\u5ea6\u503c\uff1f(GelPro\u8f6f\u4ef6\u4f7f\u7528\u65b9\u6cd5)<\/span><\/a><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDUzNTIxNA==&amp;mid=2456244074&amp;idx=1&amp;sn=f5cbff4aabcf36dce3b6429e52b77305&amp;chksm=8d7490abba0319bd2818ce0a5f6775afd2b2cac8d959ce73bf8040165e5e02b46299438e6e53&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"-webkit-tap-highlight-color: rgba(0, 0, 0, 0);cursor: pointer;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\" rel=\"noopener\">\u5b9e\u9a8c\u4e2d\u5982\u4f55\u6311\u9009\u5230\u4e00\u652f\u597d\u7528\u7684\u6297\u4f53\uff1f<\/a><\/span><\/p>\n<section style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;text-indent: 0em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img decoding=\"async\" class=\"rich_pages\" data-ratio=\"1\" data-type=\"jpeg\" data-w=\"258\" data-s=\"300,640\" data-cropsely2=\"155\" data-cropsely1=\"0\" data-cropselx2=\"154\" data-cropselx1=\"0\"  style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 155px !important;height: auto !important;\" src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-02b1fa2647f727640451312635548126.jpeg\"  \/><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u957f\u6309\u4e0a\u65b9\u4e8c\u7ef4\u7801\u5373\u53ef\u5173\u6ce8\u672c\u53f7~<\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;color: rgb(0, 0, 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src=\"http:\/\/dh.oncolab.cn\/wp-content\/uploads\/2022\/04\/wxsync-2022-04-58ffb0e373701c374fb5f9aff75cfe50.jpeg\"  \/><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u626b\u63cf\u4e8c\u7ef4\u7801\u52a0\u5165\u514d\u75ab\u4ea4\u6d41\u7fa4~<\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;white-space: normal;max-width: 100%;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 16px;widows: 1;line-height: 2em;text-align: right;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;background-color: rgb(249, 237, 166);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u70b9\u4eae\u201c\u5728\u770b\u201d<\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;white-space: normal;max-width: 100%;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 16px;widows: 1;line-height: 2em;text-align: right;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;background-color: rgb(249, 237, 166);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8ba9\u66f4\u591a\u4eba\u770b\u5230\uff01<\/span><\/section>\n<blockquote>\n<p>\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7:OncoLab<\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bfc \u8bfb \u5982\u7b2c1\u7ae0\u548c\u7b2c2\u7ae0\u6240\u8ff0\uff0c\u4eba\u7c7b\u8bc6\u522b\u5916\u6765\uff08\u975e\u81ea\u8eab\uff09\u7269\u8d28\u4e3b\u8981\u6709\u4e24\u4e2a\u7cfb\u7edf\uff1a\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u548c\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u3002 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