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Fig 9.1<\/span>\u514d\u75ab\u7403\u86cb\u767d(Ig)\u8d85\u5bb6\u65cf\u7684\u4ee3\u8868\u6210\u5458<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e00\u4e9b\u673a\u5236\u5df2\u8fdb\u5316\u5230\u4ea7\u751f\u5404\u79cd\u5404\u6837\u7684\u6297\u539f\u8bc6\u522b\u5206\u5b50–\u80fd\u591f\u4e0e\u6297\u539f\u76f8\u4e92\u4f5c\u7528\u7684\u5b8c\u6574\u7cfb\u7edf\u3002\u5c31MHC\u800c\u8a00\uff0cMHC\u5206\u5b50\u662f\u591a\u57fa\u56e0\u548c\u591a\u6001\u7684\uff1b\u4e5f\u5c31\u662f\u8bf4\uff0c\u76f8\u4f3c\u57fa\u56e0\u5b58\u5728\u591a\u4e2a\u62f7\u8d1d\u3002\u4f8b\u5982\uff0cMHC I\u7c7b\u4f4d\u70b9HLA-A\u3001HLA-B\u548cHLA-C\u3002\u5728\u4eba\u7c7b\u7fa4\u4f53\u4e2d\uff0c\u8fd9\u4e9b\u4f4d\u70b9\u4e0a\u4e5f\u5b58\u5728\u5927\u91cf\u7684\u7b49\u4f4d\u57fa\u56e0\u3002\u8fd9\u5c31\u662f\u591a\u6001\u6027\uff0c\u5373\u7fa4\u4f53\u4e2d\u4e00\u4e2a\u4f4d\u70b9\u4e0a\u5b58\u5728\u591a\u4e2a\u7b49\u4f4d\u57fa\u56e0\u3002MHC\u7684\u591a\u6001\u591a\u6837\u6027\u662f\u7531\u57fa\u56e0\u8f6c\u6362\u673a\u5236\u9020\u6210\u7684\uff0c\u5e76\u4e0d\u662fIg\u548cTCR\u57fa\u56e0\u6240\u4f7f\u7528\u7684\u4f53\u7ec6\u80de\u91cd\u7ec4\u673a\u5236\u9020\u6210\u7684\u3002\u57fa\u56e0\u8f6c\u6362\u5728\u514d\u75ab\u7cfb\u7edf\u4e2d\u5e76\u4e0d\u5e7f\u6cdb\u53d1\u751f\uff0c \u8fd9\u91cc\u4e0d\u518d\u8fdb\u4e00\u6b65\u89e3\u91ca\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Ig\u548cTCR\u57fa\u56e0\u6781\u5176\u591a\u6837\u3002\u540c\u6837\uff0c\u5c31\u50cfMHC\u7b49\u4f4d\u57fa\u56e0\u4e00\u6837–\u5728\u63a5\u89e6\u6297\u539f\u4e4b\u524d\u5c31\u5df2\u7ecf\u5b58\u5728–Ig\u548cTCR\u57fa\u56e0\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u5148\u4e8e\u63a5\u89e6\u6297\u539f\u3002\u540c\u6837\u5730\uff0c\u9176\u53c2\u4e0e\u4e86B\u548cT\u7ec6\u80de\u7684\u57fa\u56e0\u7247\u6bb5\u91cd\u7ec4\uff1a\u5305\u62ecRAG-1\u548cRAG-2\u5728\u5185\u7684V(D)J\u91cd\u7ec4\u9176\u3002\u8fd9\u4e9b\u9176\u5728\u5176\u4ed6\u7ec6\u80de\u4e2d\u4f3c\u4e4e\u4e0d\u8d77\u4f5c\u7528\u3002\u5927\u591a\u6570Ig\u548cTCR\u7684\u591a\u6837\u6027\u662fV\u533a\u57fa\u56e0\u7247\u6bb5(\u5982D\u5230J\uff0cV\u5230DJ\uff0cV\u5230J)\u91cd\u7ec4\u65f6\u4ea7\u751f\u7684\u8fde\u63a5\u591a\u6837\u6027\u7684\u7ed3\u679c\u3002Table9.1<\/span>\u4e2d\u5217\u51fa\u4e86\u5bfc\u81f4Ig\u548cTCR\u57fa\u56e0\u591a\u6837\u6027\u7684\u5404\u79cd\u9057\u4f20\u673a\u5236\u3002\u5f53\u57fa\u56e0\u7247\u6bb5\u91cd\u7ec4\u65f6\uff0c\u8fde\u63a5\u591a\u6837\u6027\u662f\u7531\u672b\u7aef\u8131\u6c27\u6838\u82f7\u9178\u8f6c\u79fb\u9176(TDT)\u7684\u63d2\u5165\u548c\u6dfb\u52a0\u6838\u82f7\u9178\u9020\u6210\u7684\uff1b\u8fd9\u663e\u7136\u662f\u9020\u6210\u8fd9\u79cd\u591a\u6837\u6027\u7684\u4e3b\u8981\u56e0\u7d20(\u88689.2<\/span>)\u3002\u53e6\u4e00\u70b9\u503c\u5f97\u5f3a\u8c03\u7684\u662f\uff0c\u6297\u539f\u514d\u75ab\u7403\u86cb\u767d\u7ed3\u5408\u4f4d\u70b9\u5728\u63a5\u89e6\u6297\u539f\u540e\u6709\u4e86\u5e7f\u6cdb\u7684\u201c\u4f18\u5316\u201d\uff0c\u800cTCR\u5728\u6297\u539f\u66b4\u9732\u540e\u5e76\u6ca1\u6709\u7ee7\u7eed\u53d8\u5316(\u89c1\u88689.1<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u6587\u7531Oncolab\u5b9e\u9a8c\u5ba4\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaImmunology for Medical Students\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span><\/p>\n


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\u2014 THE  END \u2014<\/span><\/p>\n


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\u6765\u6e90 | Immunology for Medical Students<\/span><\/section>\n
\u7ffb\u8bd1 |  \u848b\u4fca\u535a \u7f57\u4f73\u4f73<\/span><\/span><\/span><\/section>\n
\u7f16\u8f91\u6392\u7248 |<\/span> \u5f90\u66fc\u65af<\/span><\/span><\/section>\n
\u5ba1\u6838 |  \u738b\u5764 \u5b8b\u4e50<\/span><\/section>\n


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\u2589  \u5f80\u671f\u7cbe\u5f69\u5185\u5bb9\u63a8\u8350<\/strong><\/strong><\/p>\n

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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c7\u7ae0\uff1aT\u7ec6\u80de\u53d7\u4f53(TCR)\u6982\u8ff0<\/a><\/span><\/section>\n
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GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/a><\/span><\/section>\n
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PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/span><\/a>
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\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/span><\/a>
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\u5982\u4f55\u6d4b\u91cfWestern Blot\u6761\u5e26\u7070\u5ea6\u503c\uff1f(GelPro\u8f6f\u4ef6\u4f7f\u7528\u65b9\u6cd5)<\/span><\/a>
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\u70b9\u51fb\u4e0a\u65b9\u540d\u7247\u5173\u6ce8\u672c\u53f7\u83b7\u53d6\u540e\u7eed\u66f4\u591a\u7cbe\u5f69\u5185\u5bb9~<\/span><\/p>\n


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\u6b22\u8fce\u5927\u5bb6\u300c\u4e09\u8fde\u300d\uff01<\/span>
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