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3.3 CD8+<\/sup>T\u7ec6\u80de\u5728\u653e\u7597\u4e2d\u7684\u4f5c\u7528<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

3.3.1 \u653e\u5c04\u6cbb\u7597\u8bf1\u5bfc\u514d\u75ab\u53cd\u5e94<\/strong><\/p>\n<\/section>\n

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3.3.2 \u653e\u7597\u4e2d\u7684CD8+<\/sup>T\u7ec6\u80de<\/strong><\/p>\n<\/section>\n

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\u4f34\u968f\u7740T\u7ec6\u80de\u6d3b\u5316\u7684\u589e\u52a0\uff0c\u653e\u7597\u53ef\u4ee5\u4f7f\u80bf\u7624\u6d78\u6da6\u6027CD8+<\/sup>T\u7ec6\u80de\u7684TCR\u8c31\u7cfb\u591a\u6837\u5316\u3002\u6b64\u5916\uff0c\u8f90\u5c04\u8fd8\u589e\u52a0\u4e86MHC-I\u7c7b\u5206\u5b50\u7684\u8868\u8fbe\uff0c\u4fc3\u8fdb\u4e86\u65b0\u86cb\u767d\u7684\u4ea7\u751f\uff0c\u6709\u5229\u4e8e\u65b0\u6297\u539f\u7684\u5448\u9012\u3002\u53e6\u4e00\u9879\u7814\u7a76\u8868\u660e\uff0c\u8f90\u5c04\u589e\u52a0\u4e86\u764c\u75c7\u777e\u4e38\u6297\u539f\u7684\u8868\u8fbe\uff0c\u8fdb\u800c\u4fc3\u8fdb\u4e86T\u7ec6\u80de\u5bf9\u764c\u7ec6\u80de\u7684\u514d\u75ab\u8bc6\u522b\u3002\u5728\u6700\u8fd1\u7684\u4e00\u9879\u5305\u542b\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u548c\u5c0f\u9f20\u9ed1\u8272\u7d20\u7624\u6a21\u578b\u7684\u7814\u7a76\u4e2d\uff0cTCR\u6d4b\u5e8f\u663e\u793a\u9ad8\u5242\u91cf\u7684\u8f90\u5c04\u589e\u52a0\u4e86\u80bf\u7624\u6d78\u6da6\u6027CD8+<\/sup>T\u7ec6\u80de\u7684TCR\u514b\u9686\u7c7b\u578b\u7684\u591a\u6837\u6027\u3002\u7efc\u4e0a\u6240\u8ff0\uff0c\u9ad8\u5242\u91cf\u653e\u7597\u3001CTLA-4\u963b\u65ad\u548cPD-L1\u963b\u65ad\u8fd9\u4e09\u79cd\u6cbb\u7597\u65b9\u5f0f\u7684\u8054\u5408\u5e94\u7528\u5177\u6709\u6700\u4f73\u7684\u6297\u80bf\u7624\u6548\u679c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u653e\u7597\u8fd8\u53ef\u901a\u8fc7\u6539\u53d8\u80bf\u7624\u8840\u7ba1\u548c\u6539\u5584T\u7ec6\u80de\u7684\u5f52\u5de2\u6765\u4fc3\u8fdb\u80bf\u7624CD8+<\/sup>T\u7ec6\u80de\u7684\u6d78\u6da6\u3002\u8f90\u5c04\u53ef\u8bf1\u5bfc\u4fc3\u708e\u73af\u5883\uff0c\u5305\u62ec\u8bf1\u5bfc\u4ea7\u751f\u5e72\u6270\u7d20\u03b3\u4ee5\u53ca\u8bb8\u591a\u5176\u4ed6\u7684\u7ec6\u80de\u56e0\u5b50\u548c\u8d8b\u5316\u56e0\u5b50\u3002\u8fd9\u4f1a\u5bfc\u81f4\u4e0d\u540c\u514d\u75ab\u7ec6\u80de\u4e9a\u7fa4\u7684\u6d78\u6da6\uff0c\u5176\u4e2d\u5c31\u5305\u62ecCD8+<\/sup>T\u7ec6\u80de\u3002\u8f90\u5c04\u8bf1\u5bfc\u7684\u8d8b\u5316\u56e0\u5b50\u5305\u62ecCXCL9\u3001CXCL10\u3001CXCL11\u548cCXCL16\uff0c\u5b83\u4eec\u4e0eCD8+<\/sup>\u6548\u5e94T\u7ec6\u80de\u4e0a\u76f8\u5e94\u7684\u53d7\u4f53\u7ed3\u5408\uff0c\u5bfc\u81f4T\u7ec6\u80de\u5411\u80bf\u7624\u5fae\u73af\u5883\u8fc1\u79fb\u3002\u6b64\u5916\uff0c\u653e\u5c04\u6cbb\u7597\u540e\u80bf\u7624\u5185CXCL10\u7684\u4ea7\u751f\u9700\u8981I\u578b\u5e72\u6270\u7d20\u7684\u4ecb\u5bfc\u3002\u5176\u4e2d\uff0c\u653e\u5c04\u6cbb\u7597\u8bf1\u5bfc\u7684CXCL10\u8868\u8fbe\u4e0e\u7624\u5185CD8+<\/sup>T\u7ec6\u80de\u7684\u6570\u91cf\u5448\u73b0\u663e\u8457\u7684\u76f8\u5173\u6027\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n

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3.4 CD8+<\/sup>T\u7ec6\u80de\u5728\u5316\u7597\u4e2d\u7684\u4f5c\u7528<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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3.4.1 \u5316\u7597\u836f\u7269\u6fc0\u6d3b\u514d\u75ab\u53cd\u5e94<\/strong><\/p>\n<\/section>\n

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\u7ec6\u80de\u6bd2\u6027\u5316\u7597\u662f\u53e6\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u764c\u75c7\u7684\u6709\u6548\u6cbb\u7597\u65b9\u5f0f\uff0c\u7ec6\u80de\u6bd2\u6027\u5316\u7597\u901a\u8fc7\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u6b7b\u4ea1\u6216\u6291\u5236\u80bf\u7624\u7ec6\u80de\u590d\u5236\u53d1\u6325\u4f5c\u7528\u3002\u6839\u636e\u5176\u4e3b\u8981\u4f5c\u7528\u673a\u5236\uff0c\u5e38\u89c4\u5316\u7597\u836f\u7269\u53ef\u5206\u4e3a\u4ee5\u4e0b\u51e0\u7c7b\uff1a<\/p>\n

1.\u70f7\u5316\u5242\u6216DNA\u635f\u4f24\u5242\u3002\u901a\u8fc7\u5728\u7535\u8d1f\u6027\u57fa\u56e2\u4e0a\u6dfb\u52a0\u70f7\u57fa\u800c\u5bfc\u81f4DNA\u94fe\u4ea4\u8054\uff0c\u5e76\u5bfc\u81f4DNA\u635f\u4f24\uff0c\u8bf1\u5bfc\u7ec6\u80de\u6b7b\u4ea1(\u5982\u73af\u78f7\u9170\u80fa\u548c\u987a\u94c2)\u3002<\/p>\n

2.\u6297\u4ee3\u8c22\u836f\u7269\u3002\u901a\u8fc7\u6a21\u4eff\u560c\u5464\u6216\u5627\u5576\u6765\u6291\u5236DNA\u548cRNA\u7684\u5408\u6210(\u4f8b\u59825-\u6c1f\u5c3f\u5627\u5576)\u3002<\/p>\n

3.\u7eba\u9524\u4f53\u6bd2\u7d20\u3002\u5e72\u6270\u5fae\u7ba1\u529f\u80fd\u548c\u6709\u4e1d\u5206\u88c2\u7eba\u9524\u4f53\u7ec4\u88c5\uff0c\u5bfc\u81f4\u7ec6\u80de\u5468\u671f\u505c\u6ede(\u5982\u7d2b\u6749\u9187\u548c\u7d2b\u6749\u70f7)\u3002<\/p>\n

4.\u62d3\u6251\u5f02\u6784\u9176\u6291\u5236\u5242\u3002\u5728\u590d\u5236\u3001\u8f6c\u5f55\u548c\u4fee\u590d\u8fc7\u7a0b\u4e2d\u963b\u6b62DNA\u6b63\u786e\u89e3\u65cb(\u5982\u4f0a\u7acb\u66ff\u5eb7\u548c\u4f9d\u6258\u6cca\u82f7)\u3002<\/p>\n

5.\u6297\u80bf\u7624\u6297\u751f\u7d20\u3002\u7531\u571f\u58e4\u771f\u83cc\u94fe\u9709\u83cc\u7684\u5929\u7136\u4ea7\u7269\u5236\u6210\uff0c\u901a\u8fc7\u5404\u79cd\u673a\u5236\u53d1\u6325\u6297\u80bf\u7624\u4f5c\u7528\uff0c\u5305\u62ecDNA\u5d4c\u5165\u3001\u6539\u53d8\u819c\u6d41\u52a8\u6027\u548c\u4ea7\u751f\u6c27\u81ea\u7531\u57fa(\u5982\u963f\u9709\u7d20\u548c\u535a\u83b1\u9709\u7d20)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7ec6\u80de\u6bd2\u6027\u5316\u7597\u4e0e\u514d\u75ab\u7597\u6cd5\u7684\u7ed3\u5408\u662f\u51e0\u4e2a\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e3b\u9898\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e0e\u653e\u5c04\u6cbb\u7597\u76f8\u4f3c\uff0c\u7ec6\u80de\u6bd2\u6027\u5316\u7597\u5386\u6765\u88ab\u8ba4\u4e3a\u662f\u514d\u75ab\u6291\u5236\u5242\uff0c\u56e0\u4e3a\u5927\u591a\u6570\u5316\u7597\u836f\u7269\u4e0d\u52a0\u9009\u62e9\u5730\u635f\u5bb3\u7ec6\u80de\u5206\u88c2\uff0c\u4ece\u800c\u5f71\u54cd\u80bf\u7624\u7ec6\u80de\u3001\u6548\u5e94\u6dcb\u5df4\u7ec6\u80de\u548c\u5929\u7136\u767d\u7ec6\u80de\u7684\u7a33\u6001\u3002\u7ec6\u80de\u6bd2\u6027\u5316\u7597\u73b0\u5728\u662f\u5728\u8fdb\u884c\u8fc7\u7ee7\u6027\u7ec6\u80de\u6cbb\u7597\uff08\u5982HSCT \u548c ACT\uff09\u4e4b\u524d\u8fdb\u884c\u6dcb\u5df4\u7ec6\u80de\u5220\u9664\u7684\u4e3b\u8981\u624b\u6bb5\u3002\u7136\u800c\uff0c\u6700\u8fd1\u7684\u7814\u7a76\u8868\u660e\uff0c\u9009\u62e9\u4e0d\u540c\u5316\u7597\u836f\u7269\u4e5f\u53ef\u80fd\u5f71\u54cd\u6297\u80bf\u7624\u514d\u75ab\u3002\u5316\u7597\u53ef\u901a\u8fc7\u4e24\u4e2a\u4e3b\u8981\u673a\u5236\u542f\u52a8\u6216\u4fc3\u8fdb\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u3002\u9996\u5148\uff0c\u5316\u7597\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u7684\u514d\u75ab\u539f\u6027\u6b7b\u4ea1\u3002\u4e0e\u653e\u5c04\u6cbb\u7597\u76f8\u4f3c\uff0c\u5316\u7597\u5f15\u8d77\u7684ICD\u6d89\u53ca\u80bf\u7624\u6297\u539f\u7684\u91ca\u653e\u548c\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684DAMPs\u91ca\u653e\u3002\u514d\u75ab\u539f\u6027\u5316\u7597\u76f8\u5173\u7684DAMPs\u5305\u62ec\u9499\u7f51\u86cb\u767d(CRT)\u3001\u70ed\u4f11\u514b\u86cb\u767dHSP70\u548cHSP90\u3001ATP\u3001\u819c\u8054\u86cb\u767dA1\u548cHMGB1\u3002\u4e0d\u540c\u7684\u836f\u7269\u53ef\u80fd\u4e0e\u4e0d\u540c\u7684DAMPs\u76f8\u5173\uff0c\u4f8b\u5982\uff0cObeid\u7b49\u4eba\u62a5\u9053\u79f0\uff0c\u5728\u84bd\u73af\u7c7b\u836f\u7269\u8bf1\u5bfc\u7684\u7ec6\u80de\u6b7b\u4ea1\u8fc7\u7a0b\u4e2d\uff0cCRT\u66b4\u9732\u4e8e\u7ec6\u80de\u8868\u9762\u5e76\u4fc3\u8fdb\u5176\u88ab\u6811\u7a81\u72b6\u7ec6\u80de\u541e\u566c\uff0c\u4ece\u800c\u5bfc\u81f4\u80bf\u7624\u6297\u539f\u9012\u5448\u548c\u80bf\u7624\u7279\u5f02\u6027CTL\u53cd\u5e94\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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3.4.2 \u5316\u7597\u589e\u5f3aCD8+<\/sup>T\u7ec6\u80de\u7684\u6297\u80bf\u7624\u529f\u80fd<\/strong><\/p>\n<\/section>\n

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3.4.3  CD8+<\/sup>T\u7ec6\u80de\u4f7f\u80bf\u7624\u7ec6\u80de\u5bf9\u5316\u7597\u654f\u611f<\/strong><\/p>\n<\/section>\n

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3.5  \u672a\u6765\u7684\u65b9\u5411<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u53e6\u4e00\u4e2a\u6709\u5e0c\u671b\u7684\u7b56\u7565\u662f\u5c06\u514d\u75ab\u7597\u6cd5\u4e0e\u653e\u7597\u6216\u5316\u7597\u76f8\u7ed3\u5408\u3002\u8bb8\u591a\u4e34\u5e8a\u524d\u7814\u7a76\u5df2\u7ecf\u8bc1\u660e\u4e86\u5c06\u4f20\u7edf\u764c\u75c7\u7684\u6cbb\u7597\u65b9\u5f0f\u4e0e\u514d\u75ab\u6cbb\u7597\u76f8\u7ed3\u5408\u7684\u57fa\u672c\u79d1\u5b66\u539f\u7406\u3002\u4e0d\u5e78\u7684\u662f\uff0c\u8fd9\u9879\u5de5\u4f5c\u7684\u5927\u90e8\u5206\u4f9d\u8d56\u4e8e\u5177\u6709\u514d\u75ab\u80fd\u529b\u7684\u5c0f\u9f20\u6a21\u578b\uff0c\u800c\u556e\u9f7f\u52a8\u7269\u548c\u4eba\u7c7b\u5728\u514d\u75ab\u5b66\u548c\u764c\u75c7\u751f\u7269\u5b66\u4e4b\u95f4\u6709\u91cd\u8981\u7684\u533a\u522b\u3002\u514d\u75ab\u7597\u6cd5\u4e0e\u4f20\u7edf\u764c\u75c7\u7597\u6cd5\u7684\u6210\u529f\u7ed3\u5408\u9700\u8981\u7ecf\u9a8c\u7684\u8fa8\u522b\u548c\u5408\u7406\u7684\u7ed9\u836f\u3002\u4e3a\u4e86\u5f7b\u5e95\u8bc4\u4f30\u514d\u75ab\u7597\u6cd5\u4e0e\u5316\u7597\u7684\u7ed3\u5408\uff0c\u9700\u8981\u5bf9\u987a\u5e8f\u3001\u65f6\u673a\u548c\u5316\u7597\u836f\u7269\u7684\u9009\u62e9\u8fdb\u884c\u4f18\u5316\u3002\u800c\u4ece\u653e\u5c04\u6cbb\u7597\u7684\u89d2\u5ea6\u6765\u770b\uff0c\u9700\u8981\u8bc4\u4f30\u548c\u4f18\u5316\u5242\u91cf\u3001\u9776\u70b9\u548c\u65f6\u673a\u3002\u6b64\u5916\uff0c\u8fd8\u9700\u8981\u4e25\u683c\u7684\u4e34\u5e8a\u524d\u6a21\u578b\u548c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u5b9e\u73b0\u5c06\u5df2\u7ecf\u6295\u5165\u4e34\u5e8a\u7684\u6709\u6548\u7597\u6cd5\u4e0e\u7a81\u7834\u6027\u7684\u514d\u75ab\u7597\u6cd5\u76f8\u7ed3\u5408\u7684\u613f\u671b\uff0c\u901a\u8fc7\u91ca\u653eCD8+<\/sup>T\u7ec6\u80de\u7684\u6f5c\u80fd\uff0c\u5b9e\u73b0\u5bf9\u764c\u75c7\u60a3\u8005\u7684\u6700\u4f73\u75be\u75c5\u63a7\u5236\u548c\u6cbb\u6108\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u597d\u4e86\uff0c\u6211\u4eec\u672c\u671f\u7684\u5206\u4eab\u5c31\u5230\u8fd9\u91cc\uff0c\u4e0b\u671f\u518d\u89c1!<\/p>\n

\u7531\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\u63a8\u9001\u89c4\u5219\u53d8\u5316\uff0c\u4e3a\u4e86\u80fd\u591f\u53ca\u65f6\u6536\u5230\u6211\u4eec\u7684\u63a8\u9001\uff0c\u5efa\u8bae\u591a\u591a\u70b9\u8d5e\u3001\u5728\u770b\u3001\u6536\u85cf\u5e76\u6dfb\u52a0\u661f\u6807\u54e6~~~<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u6587\u7531Oncolab\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaOncoimmunology: A Practical Guide for Cancer Immunotherapy\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u2014 THE  END \u2014<\/span><\/p>\n


<\/p>\n

\u6765\u6e90 | Oncoimmunology: A Practical Guide <\/span><\/section>\n
for Cancer Immunotherapy<\/span><\/section>\n
\u4f5c\u8005 | Weimin Wang, Michael Green, J. Rebecca Liu, <\/span><\/section>\n
Theodore S. Lawrence, and Weiping Zou<\/span><\/section>\n
\u7ffb\u8bd1 |   \u90d1\u68a6\u6021 \u9648\u8389\u8679 \u949f\u96ea\u83b9<\/span><\/section>\n
\u7f16\u8f91\u6392\u7248 | \u9648\u6653\u610f<\/span><\/span><\/section>\n
\u521d\u5ba1 | \u5b8b\u4e50 \u9648\u79cb\u8c37<\/span><\/section>\n
\u7ec8\u5ba1 | \u738b\u5764<\/span> \u8096\u5efa\u52c7<\/span><\/section>\n
\uff08\u8f6c\u8f7d\u8bf7\u4fdd\u7559\u6b64\u90e8\u5206\u5185\u5bb9\uff09<\/span><\/strong><\/section>\n

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\u2589  \u5f80\u671f\u6587\u7ae0\u76ee\u5f55<\/strong><\/strong><\/p>\n

\u57fa\u7840\u514d\u75ab\u5b66\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c23\u7ae0\uff1a\u708e\u75c7\u4e0e\u514d\u75ab<\/span><\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c22\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u6740\u4f24\u529f\u80fd<\/span><\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c21\u7ae0\uff1a\u541e\u566c\u7ec6\u80de<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c20\u7ae0\uff1a\u56fa\u6709\u514d\u75ab\u7684\u9632\u5fa1\u4f5c\u7528<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c19\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u751f\u7406\u529f\u80fd\u7b80\u8ff0<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c18\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u8c03\u8282<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c17\u7ae0\uff1a\u514d\u75ab\u8bb0\u5fc6\u4e0e\u6dcb\u5df4\u7ec6\u80de\u7a33\u6001<\/span><\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c16\u7ae0\uff1aT\u7ec6\u80de\u4e0e\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\u95f4\u7684\u76f8\u4e92\u4f5c\u7528<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c15\u7ae0\uff1aT\u7ec6\u80de\u7684\u53d1\u80b2<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c14\u7ae0\uff1aB\u7ec6\u80de\u7684\u53d1\u80b2<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c13\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u5668\u5b98\u548c\u7ec4\u7ec7<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c12\u7ae0\uff1a\u9020\u8840\u529f\u80fd-\u8840\u7ec6\u80de\u751f\u6210<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c11\u7ae0\uff1a\u6dcb\u5df4\u7ec6\u80de\u6d3b\u5316<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c10\u7ae0\uff1a\u6297\u539f\u7684\u5904\u7406\u548c\u5448\u9012<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c9\u7ae0\uff1a\u6297\u539f\u8bc6\u522b\u7814\u7a76\u8fdb\u5c55<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c8\u7ae0\uff1a\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269MHC<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c7\u7ae0\uff1aT\u7ec6\u80de\u53d7\u4f53(TCR)\u6982\u8ff0<\/a>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c6\u7ae0\uff1a\u6297\u4f53\u591a\u6837\u6027<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c5\u7ae0\uff1a\u6297\u4f53-\u6297\u539f\u76f8\u4e92\u4f5c\u7528<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c4\u7ae0\uff1a\u6297\u539f\u548c\u6297\u4f53\u7ed3\u6784<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c3\u7ae0\uff1a\u6297\u539f\u8bc6\u522b<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c2\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u57fa\u672c\u6982\u5ff5\u548c\u7ec4\u6210<\/a><\/span>
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\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c1\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7b80\u4ecb<\/a><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c3\u7ae0\uff1aCD8+ T\u7ec6\u80de\u5728\u514d\u75ab\u6cbb\u7597\u3001\u653e\u7597\u548c\u5316\u7597\u4e2d\u7684\u4f5c\u7528\uff08\u4e0a\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c2\u7ae0\uff1a\u4eba\u7c7b\u80bf\u7624\u5fae\u73af\u5883\uff08\u4e0b\uff09<\/span><\/a>
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\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c2\u7ae0\uff1a\u4eba\u7c7b\u80bf\u7624\u5fae\u73af\u5883\uff08\u4e0a\uff09<\/a><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c1\u7ae0\uff1a\u80bf\u7624\u514d\u75ab\u7b80\u53f2<\/a><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c7\u5929)-210608<\/a>
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\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c6\u5929)-210607<\/a>
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\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c5\u5929)-210605<\/a>
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\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c4\u5929)-210604<\/a><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c3\u5929)-210603<\/span><\/a>
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\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c1\u5929)-20210531<\/a><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c2\u5929)-20210601<\/a><\/p>\n

TCGA\u514d\u75ab\u6d78\u6da6\u8bc4\u4ef7\u6570\u636e\u5e93<\/a>
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ggplot2|\u8be6\u89e3\u516b\u5927\u57fa\u672c\u7ed8\u56fe\u8981\u7d20<\/a>
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Python\u96c6\u6210\u5f00\u53d1\u73af\u5883PyCharm\u7684\u5b89\u88c5\u4e0e\u6fc0\u6d3b<\/a>
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Python\u53d1\u884c\u7248Anaconda\u7684\u5b89\u88c5\u4e0e\u4f7f\u7528<\/a><\/p>\n

\u57fa\u7840\u5b9e\u9a8c\u6280\u672f\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u6d41\u5f0f\u68c0\u6d4b\u7ec6\u80de\u603bROS-OncoLab\u5b9e\u9a8c\u5ba4<\/a><\/span>
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Annexin V\/PI\u67d3\u8272\u68c0\u6d4b\u7ec6\u80de\u51cb\u4ea1-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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\u514d\u75ab\u8367\u5149\u5b9e\u9a8c-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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WB\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/a><\/span><\/p>\n

QPCR\u5b9e\u9a8c\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
<\/p>\n

\u4eea\u5668\u64cd\u4f5c\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u5c0f\u52a8\u7269\u6d3b\u4f53\u5149\u5b66\u6210\u50cf\u7cfb\u7edf\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a>
<\/p>\n

\u8521\u53f8LSM800\u6fc0\u5149\u5171\u805a\u7126\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a>
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IN Cell Analyzer2200\u9ad8\u5185\u6db5\u7ec6\u80de\u6210\u50cf\u5206\u6790\u7cfb\u7edf\u64cd\u4f5c\u6559\u7a0b-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a>
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BD LSR Fortessa\u6d41\u5f0f-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a><\/span><\/p>\n

\u6587\u732e\u5206\u4eab\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u80bf\u7624\u4ee3\u8c22\u91cd\u7f16\u7a0b\u4e0e\u514d\u75ab\u5e94\u7b54<\/a>
<\/p>\n

\u5e74\u5ea6\u5de8\u732e\uff1a\u795e\u520aCA\u53d1\u5e03\u6700\u65b0\u764c\u75c7\u6570\u636e\uff1a\u5168\u74031000\u4e07\u4eba\u6b7b\u4e8e\u764c\u75c7\uff0c\u4e2d\u56fd\u5360\u6bd4\u8d853\u6210<\/a>
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HLA-I\u5206\u5b50\u52a0\u5de5\u548c\u9012\u5448\u6297\u539f\u529f\u80fd\u53d7\u635f\u662f\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8010\u836f\u7684\u91cd\u8981\u539f\u56e0<\/a>
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PD-1\/PD-L1\u963b\u65ad\u5242\u6cbb\u7597\u80bf\u7624\u7684\u7814\u7a76\u8fdb\u5c55\u4e0e\u9762\u4e34\u7684\u6311\u6218<\/a><\/span><\/p>\n

Immunity\uff1a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u5341\u5927\u6311\u6218<\/span><\/a><\/p>\n

\u4f5c\u56fe\u6295\u7a3f\u9009\u520a\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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\u5982\u4f55\u4f7f\u7528ImageJ\u8fdb\u884c\u7ec6\u80de\u8367\u5149\u5b9a\u91cf<\/a>
<\/p>\n

\u5982\u4f55\u4f7f\u7528Scrivener\u8fdb\u884c\u79d1\u6280\u8bba\u6587\u5199\u4f5c<\/a>
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Mendeley-\u6700\u597d\u7528\u7684\u6587\u732e\u9605\u8bfb\u7ba1\u7406\u8f6f\u4ef6\uff0c\u6ca1\u6709\u4e4b\u4e00<\/a>
<\/p>\n

\u5982\u4f55\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u7684\u6742\u5fd7\u8fdb\u884c\u6295\u7a3f\uff1f<\/a>
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PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/a>
<\/p>\n

\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/a><\/span><\/p>\n

\u4e2d\u533b\u4e2d\u836f\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u516b\u6bb5\u9526\uff08\u89c6\u9891\u7248+\u56fe\u7247\u7248\uff0c\u63a8\u8350\u6536\u85cf\uff09<\/span><\/a>
<\/p>\n

\u4e2d\u6210\u836f\u4f20\u7edf\u65b9\u5242\u4ea4\u53c9\u68c0\u7d22\u6570\u636e\u5e93\u4f7f\u7528\u8bf4\u660e<\/span><\/a>
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